Protein Alignment anne and CG6230

DIOPT Version :9

• Sequence 1: NP_001096849.1
• Gene: anne / 317815
• FlyBaseID: FBgn0052000
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: NP_609490.1
• Gene: CG6230 / 34546
• FlyBaseID: FBgn0027582
• Length: 1225
• Species: Drosophila melanogaster
• Alignment Length: 1341
• Identity: 327/1341 - (24%)
• Similarity: 539/1341 - (40%)
• Gaps: 375/1341 - (27%)

  Fly   187 LLRLVLHWWRHLYLYATCSQCSLEEAEQVLVTEDYQGKHKMYHVKQIQVLTSSNLKTLLEKEQQS 251
            |..|..:|..|:..:.||.:..|..|..:              .|.:....:.|.|.
  Fly   120 LTLLFCYWSVHVLAFLTCRRVKLPGANVL--------------AKVVPTPNNGNSKI-------- 162

  Fly   252 IERTHIECDHVENVLQLSVHFTSAQFKKCSSIRIFRCKQLVYAWNNNTNRFQR----INGLDLNI 312
                              |...|::.:..|:...|..::..|.||.:...|:.    :|||
  Fly   163 ------------------VPIRSSKLEDGSTQYYFVFQKTKYVWNEDRKTFRAVEFPVNGL---- 205

  Fly   313 PCSYYHQQRGLPVHEQISRRI-VFGDNEITVPLRDFKTLLFLEVLNPFYVFQLFSVILWFTYDYY 376
             .|.|...|||...|.|.|.. .:|:||:.:.:.:|..|.......||:|||:|||.||...||:
  Fly   206 -LSTYSSSRGLETEEDIKRATQTYGNNEMEMVVPEFHELFIERATAPFFVFQVFSVGLWCMDDYW 269

  Fly   377 YYACVILLMSV-FGITVSVLQTKKNQDVLQK------TVYN-TGNAWVVDHKGLSKELPTRAIVP 433
            ||:...|.|.: |..|: |.|..:|...::|      .:|. ..|.|        :.|.:..::|
  Fly   270 YYSLFTLFMLIAFECTI-VKQQLRNMSEIRKMGNKPYLIYAFRQNKW--------RHLGSDELLP 325

  Fly   434 GDIIEIPSS--GCTLHCDAILISGNCILDESMLTGESVPVTKTPLPS--KRDMIFDKTEHAR-HT 493
            ||::.|..|  ...:.||.:::.|:||:|||||||||||:.|..|.|  ..|:..|.....: ..
  Fly   326 GDLVSITRSQNDNIVPCDLVILRGSCIVDESMLTGESVPLMKESLESLDNLDVEMDAEGDGKLFV 390

  Fly   494 LFCGTKVIQTRYIGSKKV-------LAFVINTGNITAKGELIRSILYPPPVDYKFEQDSYKFIQF 551
            ||.||||:|......:.:       :.:||.||..|::|:|:|:||:......:...:::.||.|
  Fly   391 LFGGTKVVQHTAPTKESLRAPDGGCIGYVIRTGFNTSQGKLLRTILFGANRATENNVETFAFIAF 455

  Fly   552 LAIIACVGFIYTLVTKILRGT-DP----VKIAVESLDLITIVVPPALPAAMTVGRFYAQKRLKTS 611
            |.:.|.....|..|    :|: ||    .|:.:|...::|.::||.||..:|:....:..:|...
  Fly   456 LMVFAVAAASYVWV----KGSEDPERNRYKLFLECTLILTSIIPPDLPIELTLAVNTSLIQLTKL 516

  Fly   612 EIFCISPRSINVAGSINCCCFDKTGTLTEDGLDMWGV-----------VPKSSTNQFQIPLKSVD 665
            .:||..|..|..||.:..||||||||||.|.|.:.|:           :.|:..|..|:
  Fly   517 FVFCTEPFRIPFAGKVQICCFDKTGTLTTDNLMVEGIAGLAPNGACVPIEKAEGNTVQV------ 575

  Fly   666 RLPFDHFLFGMVTCHSITILNGRMMGDPLDLKMFESTGWELEDSNNIPDTEKYGILYPTILRQPR 730
                      :..|||:.:|:..::||||:.....:..|.|...:::            |.::|:
  Fly   576 ----------LACCHSLALLDDGLVGDPLEKATLAAVDWTLTKMDSV------------IPKRPQ 618

  Fly   731 GGLSGMAETESGSKNEIKRQSSVDDLLATVGISPSQKNFDHGIVREFPFTSALQRMSVVTRCL-- 793
                                           ..|.:      |::.:.|:|||:||||:...|
  Fly   619 -------------------------------FKPLK------IIQRYHFSSALKRMSVLAGHLIP 646

  Fly   794 -SDQVFNV-YCKGSPEMLKKLCKPQSLPDNYSQQLSEFAKKGYRIIAIAFKALSHKMNYTKVQRL 856
             |::|.:: ..||:||:::|:.:  .:|.:|.:...|:|::|.|::|:..|.|. .:...:|:.:
  Fly   647 YSNEVKHIGAVKGAPEVIQKMLR--EVPADYEKVYLEYARRGARVLALGIKDLG-TLGAQRVREM 708

  Fly   857 SREEVENNMEFLGFVILENRLKPDTTKVINALNAAKIRTIMITGDNILTAISVARDCGIVSPSQS 921
            .|||||.::.|.||:|:...:|||:..||..|..:..:.:|||||:.|||..|||:.........
  Fly   709 KREEVECDLTFAGFLIISCPMKPDSKSVIKELIQSSHKVVMITGDSPLTACHVARELRFTRKKLI 773

  Fly   922 VITVHADPIGDSANIQTNTGTECNFDNSSDKHYKLHYTLDLGSKTSRAYLFKSCFNSNLFDPETP 986
            ::|   .|..|    :.|..:..:.|  .|:.|:|.
  Fly   774 ILT---PPEED----RKNNWSWVSID--GDQSYELD----------------------------- 800

  Fly   987 EFTAQVGKTIFHMESTNSLVNESTSSYAESGLPTSDSLASVKTIDTWTHNDAELGIKHTPDESWR 1051
              |....|.:.|:.:|:.|
  Fly   801 --TKPGSKKLSHLLATHDL---------------------------------------------- 817

  Fly  1052 RQECIFAMDGKTWQIVKDYFPEEMEILLTRGSIYARMSPDQKQALVIELQNLDYCVAMCGDGAND 1116
               ||   .|:..|.::...|:.|..||.:.::.||.:|.||:.::.:|:.|.||..|||||.||
  Fly   818 ---CI---TGEGLQYLQQNQPQYMRQLLPQITVCARFAPKQKELVITQLKQLGYCTLMCGDGTND 876

  Fly  1117 CGALKVAHAGIS---------------------------------------------------LS 1130
            .||||.|:.|:|                                                   |:
  Fly   877 VGALKHANVGVSLLTSAPVKRKRTEEEQQQAAANAAAIAAQAQANANQQLTTRERALRRRQEHLN 941

  Fly  1131 ET--------------------EASIASPFTSRNPTISAVLKVIKEGRAALVTSFGIFKYMAAYS 1175
            :|                    :||||:||||::.:|..|..:||:||..|||:..:||.:|..:
  Fly   942 QTQARLQNALRDMEEQTMVKLGDASIAAPFTSKSSSIMCVNHIIKQGRCTLVTTLQMFKILALNA 1006

  Fly  1176 LVQFISVMILYSIDSNLTDKQYLYVDLGLISIFAFFFGKTESFDGMLVEQVPLSSLISSTPLASL 1240
            |:|.....:||......:|.|.....:.:.:.|.|           :....||.:|....||.::
  Fly  1007 LIQAYCQSVLYIDGIKFSDTQATMQGIFIAACFLF-----------ITRAKPLKTLSKVAPLPNI 1060

  Fly  1241 LLHLTVV-----------TAFQVTCWVHLHQQP---WFKAFEPADEDHLGCFENYTMFCISSFQY 1291
            ....|:.           |.:.:|...::...|   ..|.:...|.:..   ..|....:||..|
  Fly  1061 FNFYTISTILSQFAVHFGTLYYLTSQANILAPPREGKVKLYIDMDAEEK---TKYDPNIVSSTVY 1122

  Fly  1292 II-------LAFVFSKGAPYRKPLWSNWPLCLAFIVNLCIIVYLVLYPSDWVASFFQLIVPPTMR 1349
            ||       ...|..||.|:.:.|.||..|..|...:..:::.|....:..:..||::|..|| .
  Fly  1123 IICLSLQVATIAVNYKGYPFMESLRSNRMLMYAIGASAALVILLSTGLAPELTEFFEIIDFPT-D 1186

  Fly  1350 FRYVMLAYGAASFICHIFVESFLVEYLVFKKYQVKREKNWV 1390
            ||..:|..    .:..| |.:||::.:....:...|.|:.|
  Fly  1187 FRKTLLGV----LVLDI-VGAFLLDRICSFLFGETRRKSKV 1222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
anne	NP_001096849.1	P5-ATPase	158..291	CDD:289194	15/103 (15%)
		P-ATPase-V	173..1355	CDD:273738	319/1304 (24%)
		E1-E2_ATPase	381..621	CDD:278548	77/264 (29%)
		Cation_ATPase	<758..813	CDD:289987	18/58 (31%)
		HAD_like	<1087..1137	CDD:304363	26/120 (22%)
CG6230	NP_609490.1	P-ATPase-V	109..1193	CDD:273738	319/1305 (24%)
		E1-E2_ATPase	310..515	CDD:278548	65/216 (30%)
		Cation_ATPase	<590..664	CDD:289987	25/122 (20%)
		COG4087	<850..901	CDD:226572	21/50 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438604
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D172453at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45630
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950