Protein Alignment anne and cta5

DIOPT Version :10

• Sequence 1: NP_001096849.1
• Gene: anne / 317815
• FlyBaseID: FBgn0052000
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: NP_594863.1
• Gene: cta5 / 2542076
• PomBaseID: SPAC29A4.19C
• Length: 1096
• Species: Schizosaccharomyces pombe
• Alignment Length: 1213
• Identity: 328/1213 - (27%)
• Similarity: 536/1213 - (44%)
• Gaps: 216/1213 - (17%)

  Fly   183 LTGGLLRLVLHWWRHLYLYATCSQCSLEEAEQVLVTEDYQGKHKMYHVKQIQVLTSSNLKTLLEK 247
            ||.|||.|:|.|.....|....:.||.|:.|.|.:: |..|             ||
pombe    57 LTLGLLHLILTWLPEFRLKWIEAPCSNEDVEFVAIS-DPSG-------------TS--------- 98

  Fly   248 EQQSIERTHIECDHVENVLQLSVHFTSAQFKKCSSIRIFRCKQLVYAWNNNTNRFQRINGLDLN- 311
               |||:....|  ::|.:|     ||:........|.|..|:|         ||. :..|:|.
pombe    99 ---SIEKVSSIC--LKNDIQ-----TSSFVLPSGKTRYFEYKKL---------RFY-LEPLNLQW 143

  Fly   312 ----IPCSYY--------HQQRGLPVHEQISRRIVFGDNEITVPLRDFKTLLFLEVLNPFYVFQL 364
                :..|.|        :.|.||........|.|:|.|.:....:...|:|..|||:|||:||.
pombe   144 VLMPLETSAYSLVTSTPAYIQNGLDTFTIAKLRQVYGSNSLVSTKKSIVTILLNEVLHPFYLFQA 208

  Fly   365 FSVILWFTYDYYYYACVILLMSVFGITVSVLQTKKNQDVLQKTVYNTGNAWVVDHKGLSKELPTR 429
            .||::|....:.:|:|.|:.:|.:.|.:||.::|::::.:...:.......|:.:: :.:.:...
pombe   209 VSVLIWLCDSFVFYSCCIVFISSYSIFLSVKESKESENRIHSIIGAPQPVTVIRNQ-VKQTVLAD 272

  Fly   430 AIVPGDIIEIPSSGC-TLHCDAILISGNCILDESMLTGESVPVTKTPL-PSKRD--MIFDKTEHA 490
            .:|.||::...:... |...|.||.|.:|:|||||:||||||..|.|| .:..|  ||......:
pombe   273 DLVIGDLLYFSNLDLKTCPVDGILFSSSCLLDESMVTGESVPARKFPLEDNSLDSWMIASCNIFS 337

  Fly   491 RHTLFCGTKVIQTRYIGSKKVLAFVINTGNITAKGELIRSILYPPPVDYKFEQDSYKFIQFLAII 555
            .|.:..|||.::.....|...|..|:.||..:.||:|||::|||.....:...||..|::.:||:
pombe   338 PHLIHAGTKFLKIDSTPSTPCLISVVRTGFRSNKGQLIRNLLYPNLRPSQLYLDSMSFLKTMAIL 402

  Fly   556 ACVGFIYTLVTKILRGTDPVKIAVESLDLITIVVPPALPAAMTVGRFYAQKRLKTSEIFCISPRS 620
            :.|..::..:...|.......:.:.|||::||:|||||||.::||...:..||..:.|:..||.|
pombe   403 SFVSIVFIAIYLNLYNASFGHVVLRSLDVLTILVPPALPATLSVGIANSIARLSRALIYTTSPES 467

  Fly   621 INVAGSINCCCFDKTGTLTEDGLDMWGVVPKSSTN----QFQIPLKSVDRLPFDHFLFGMVTC-H 680
            |:.||.::...|||||||||:.:.:..|..||.:|    |......|:|....:...:.:.|| .
pombe   468 IHNAGCLSTFVFDKTGTLTENSVQLSCVYVKSGSNGLLKQVDADSLSLDSTKLNAHAYRVATCSQ 532

  Fly   681 SITILNGRMMGDPLDLKMFESTGWELEDSNNIPDTEKYGILYPTI--LRQPRGGLSGMAETESGS 743
            |:.::...::||||::.:|               |:..|....||  ...|...|..::.:..|
pombe   533 SLELVGNELVGDPLEVTLF---------------TQFNGTFCATIRASNTPHPPLFSVSNSFDG- 581

  Fly   744 KNEIKRQSSVDDLLATVGISPSQKNFDHGIVREFPFTSALQRMSVVTRCLSDQVFNVYCKGSPEM 808
                                |||   ...|.:...|...|:||||:....:::...::.||:||.
pombe   582 --------------------PSQ---IFSIYKALEFDPVLRRMSVICSTSTERSLMLFTKGAPES 623

  Fly   809 LKKLCKPQSLPDNYSQQLSEFAKKGYRIIAIAFKALSHKMNYTKVQ---RLSREEVENNMEFLGF 870
            :..:...||:|.|..:.:...:.||:||||.|.|.|     .|.:|   .|||..:|:|:.|.|.
pombe   624 ILAISSQQSIPSNVQEVIHTLSSKGFRIIAFASKNL-----ITPLQELIHLSRSTLESNVTFQGL 683

  Fly   871 VILENRLKPDTTKVINALNAAKIRTIMITGDNILTAISVARDCGIVSPSQSVITVHADPIGDSAN 935
            .:||:.|:..:..||::|..:|:...:.:||::.|::.||:.||.:.....:.|..   :.||
pombe   684 FVLESPLRESSKDVISSLLRSKMEVSICSGDSLFTSVFVAKHCGALDSCNFIYTAE---LADS-- 743

  Fly   936 IQTNTGTECNFDNSSDKHYKLHY-TLDLGSKTSRAYLFKSCFNSNLFDPETPEFTAQVGKTIFHM 999
                 |.:|.         ::|: .:||.::.              |.|
pombe   744 -----GDDCP---------QIHFEKIDLQTQN--------------FQP---------------- 764

  Fly  1000 ESTNSLVNESTSSYAESGLPTSDSLASVKTIDTWTHNDAELGIKHTPDESWRRQECIFAMDGKTW 1064
                              :|...||.     |.....|:.|                 .||||..
pombe   765 ------------------IPDGFSLK-----DVILEKDSSL-----------------CMDGKLL 789

  Fly  1065 QIVKDYFP-EEMEILLTRGSIYARMSPDQKQALVIELQNLDYCVAMCGDGANDCGALKVAHAGIS 1128
            |.:..... .|::|||::..:.|||||..|...|...|.....|..||||||||.|||.|..|:|
pombe   790 QRLLTMLSFNEIKILLSKLRVLARMSPFDKATYVELCQKYGCKVGFCGDGANDCIALKQADVGVS 854

  Fly  1129 LSETEASIASPFTSRNPTISAVLKVIKEGRAALVTSFGIFKYMAAYSLVQFISVMILYSIDSNLT 1193
            ||::||..|:.|.|:..:|..|..|:.|||.:|:.|...|:||...::|||..|..||..:.|..
pombe   855 LSDSEACAAASFVSKKKSIKDVFNVLLEGRCSLILSHRCFQYMVLCAIVQFSGVFFLYLKNYNFN 919

  Fly  1194 DKQYLYVDLGLI---SIFAFFFGKTESFDGMLVEQVPLSSLISSTPLASLLLHLTVVTAFQVTCW 1255
            |.|:|::||.:|   |....:|...::    |....|.|:|.....:..|.:...::........
pombe   920 DNQFLFMDLLIIFPLSAAMSYFDPAQN----LTSNRPNSTLFGKGRVKDLGIQSVLIWLSHGLLT 980

  Fly  1256 VHLHQQPWFKAFE-PADEDHLGCFENYTMFCISSFQYIILAFVFSKGAPYRKPLWSNWP-LCLAF 1318
            :.||:..|.:..| ..::.:.......::|.:||.||:.:....::.:.:..|:|.... :||..
pombe   981 LILHELNWVELPEWQLEKSNTKNVLVTSIFLLSSLQYLGICIGINQSSEFLSPIWKKKTYVCLCT 1045

  Fly  1319 IVNLCIIVYLVLYPSDWVASFFQLIVPPTMRFRYVMLAYGAAS 1361
            .:.||.|.......:..::...|:...||: :|:::|..|..|
pombe  1046 TIGLCNIYLCFANENHIISRCLQITRLPTL-YRFIILFMGVIS 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
anne	NP_001096849.1	P5-ATPase	158..296	CDD:463565	30/112 (27%)
		P-type_ATPase_cation	326..1281	CDD:319842	270/974 (28%)
cta5	NP_594863.1	P-ATPase-V	33..1083	CDD:273738	326/1207 (27%)