Protein Alignment anne and catp-8

DIOPT Version :9

• Sequence 1: NP_001096849.1
• Gene: anne / 317815
• FlyBaseID: FBgn0052000
• Length: 1451
• Species: Drosophila melanogaster
• Sequence 2: NP_502165.2
• Gene: catp-8 / 178070
• WormBaseID: WBGene00007514
• Length: 1178
• Species: Caenorhabditis elegans
• Alignment Length: 1360
• Identity: 321/1360 - (23%)
• Similarity: 514/1360 - (37%)
• Gaps: 388/1360 - (28%)

  Fly   162 MKVCGYRRSLMRTGFCWACIFLTGGLLRLVLHWWRHLYLYATCSQCSLEEAEQVLVTEDYQGKHK 226
            :.:.||..........:|.||:...|:.|..||...:..:..||     :.|.|.:..
 Worm    39 LNIFGYEEYYELGMLGYAAIFVILALVLLFCHWMMPVRCFLMCS-----KQEDVRIAS------- 91

  Fly   227 MYHVKQIQVLTSSN--------LKTLLEKEQQ---SIERTHIECDHVENVLQLSVHFTSAQFKKC 280
              ||..|.  |.:|        ::|..:|:.:   ..:|.|
 Worm    92 --HVCVIP--TQNNGWPELVKLMRTTRDKQTKLWFEFQRVH------------------------ 128

  Fly   281 SSIRIFRCKQLVYAWNNNTNRFQRINGLDLNIPCSYYHQQRGLPVHEQI-SRRIVFGDNEITVPL 344
                        |.|:..:..|| ...||...|..::.:..|..|.|.: ..:.:.|||:..:.:
 Worm   129 ------------YTWDEESREFQ-TKTLDTAKPMVFFQKSHGFEVEEHVKDAKYLLGDNKTEMIV 180

  Fly   345 RDFKTLLFLEVLNPFYVFQLFSVILWFTYDYYYYACVILLMSVFGITVSVLQTKKNQDVLQKTVY 409
            ..|..:.......||:|||:|.|.||...|.:||:...|.|.:......|.|..||...::....
 Worm   181 PQFLEMFIERATAPFFVFQVFCVGLWCLEDMWYYSLFTLFMLMTFEATLVKQQMKNMSEIRNMGN 245

  Fly   410 NT-------GNAWVVDHKGLSKELPTRAIVPGDIIEI---PSSGCTLHCDAILISGNCILDESML 464
            .|       |..|        :::....:|.|||:.|   ....| :.||.:|:.|.||:|||||
 Worm   246 KTYMINVLRGKKW--------QKIKIEELVAGDIVSIGRGAEEEC-VPCDLLLLRGPCIVDESML 301

  Fly   465 TGESVPVTKTPLPS-KRDMIFD-KTEHARHTLFCGTKVIQTRYIGSK----------KVLAFVIN 517
            ||||||..|.|:.. ::|.||| :|:...|.:|.|||::|....|..          ..:.:||.
 Worm   302 TGESVPQMKEPIEDVEKDKIFDIETDSRLHVIFGGTKIVQHTAPGKAAEGMVKSPDGNCICYVIR 366

  Fly   518 TGNITAKGELIRSILYPPPVDYKFEQDSYKFIQFLAIIACVGFIYTLVTKILRGT-DPVKIAVES 581
            ||..|::|:|:|:|::..........:::.||.||.|.|.....|..:...:..| ...|:.:|.
 Worm   367 TGFNTSQGKLLRTIMFGVKKATANNLETFCFILFLLIFAIAAAAYLWIKGSVDETRSKYKLFLEC 431

  Fly   582 LDLITIVVPPALPAAMTVGRFYAQKRLKTSEIFCISPRSINVAGSINCCCFDKTGTLTEDGLDMW 646
            ..::|.|:||.||..:::....:...|:...|||..|..|..||.::.||||||||||.|.|.:.
 Worm   432 TLILTSVIPPELPIELSLAVNSSLMALQKLGIFCTEPFRIPFAGKVDICCFDKTGTLTTDNLVVE 496

  Fly   647 GVVPKSSTNQFQIPLKSVDRLPFDHFLFGMVTCHSITILNGRMMGDPLDLKMFESTGWELEDSNN 711
            ||   :..||.:..:::.:.||.:. |..:.:|||:......::||||:.......||.|...:.
 Worm   497 GV---ALNNQKEGMIRNAEDLPHES-LQVLASCHSLVRFEEDLVGDPLEKACLSWCGWNLTKGDA 557

  Fly   712 I--PDTEKYGILYPTILRQPRGGLSGMAETESGSKNEIKRQSSVDDLLATVGISPSQKNFDHGIV 774
            :  |.|...||                    ||.|                            |.
 Worm   558 VMPPKTAAKGI--------------------SGIK----------------------------IF 574

  Fly   775 REFPFTSALQRMSVV----TRCLSDQVFNVYCKGSPEMLKKLCKPQSLPDNYSQQLSEFAKKGYR 835
            ..:.|:||::||:||    :...||..|.|..||:||:|:.:.  ..||.:|.:..:...::|.|
 Worm   575 HRYHFSSAMKRMTVVAGYQSPGTSDTTFIVAVKGAPEVLRNMY--ADLPSDYDETYTRLTRQGSR 637

  Fly   836 IIAIAFKALSHKMNYTKVQRL---SREEVENNMEFLGFVILENRLKPDTTKVINALNAAKIRTIM 897
            ::|:..:    |:..|:|..|   .||..||::.|.|||::...||.||..:|..:..:.....|
 Worm   638 VLAMGIR----KLGETRVGELRDKKRENFENDLAFAGFVVISCPLKSDTKTMIREIMDSSHVVAM 698

  Fly   898 ITGDNILTAISVARDCGIVSPSQSVITVHADPIGDSANIQTNTGTECNFDNSSDKHYKLHYTLDL 962
            |||||.|||..|::.......|...:.:.....|.....::..||               ..|.|
 Worm   699 ITGDNPLTACHVSKVLKFTKKSLPTLVLDEPADGVDWMWKSVDGT---------------IELPL 748

  Fly   963 GSKTSRAYLFKSCFNSNLFDPETPEFTAQVGKTIFHMESTNSLVNESTSSYAESGLPTSDSLASV 1027
            ..:|......|:.|||:.|        ...|....|:
 Worm   749 KPETKNKMERKAFFNSHEF--------CLTGSAFHHL---------------------------- 777

  Fly  1028 KTIDTWTHNDAELGIKHTPDESWRRQECIFAMDGKTWQIVKDYFPEEMEILLTRGSIYARMSPDQ 1092
                  .||:      ||                         |..|   |:....::|||:|.|
 Worm   778 ------VHNE------HT-------------------------FLRE---LILHVKVFARMAPKQ 802

  Fly  1093 KQALVIELQNLDYCVAMCGDGANDCGALKVAHAGISL----------SETE-------------- 1133
            |:.::.||::|.....|||||.||.||||.|:.|::|          :|.|
 Worm   803 KERIINELKSLGKVTLMCGDGTNDVGALKHANVGVALLTNPYDAEKAAEKEKEKKAKIEEARSLV 867

  Fly  1134 ----------------------------------------------------------------- 1133
                                                                             
 Worm   868 RSGAQLPQRPGAPGAPPAANAARRDAPPGARARAPLPPMANAAQARLDNLMKELEEEEKAQVIKL 932

  Fly  1134 --ASIASPFTSRNPTISAVLKVIKEGRAALVTSFGIFKYMAAYSLVQFISVMILYSIDSNLTDKQ 1196
              ||||:||||:..:|:::..|||:||..|||:..:||.:|..:||...|:..||......:|.|
 Worm   933 GDASIAAPFTSKYTSIASICHVIKQGRCTLVTTLQMFKILALNALVSAYSLSALYLDGVKFSDTQ 997

  Fly  1197 YLYVDLGLISIFAFFFGKTESFDGMLVEQVPLSSLISSTPLASL-----LLHLTVVTAFQVTCWV 1256
            .....|.|.:.|.|           :.:..||.:|....|:|::     ||.:|:......:|.:
 Worm   998 ATIQGLLLAACFLF-----------ISKSKPLKTLSRQRPMANIFNAYTLLTVTLQFIVHFSCLL 1051

  Fly  1257 HL----HQQPWFKAFEPADEDHLGCFENYTMFCISSFQYIILAFVFSKGAPYRKPLWSNWPLCLA 1317
            ::    |:....||....:........|.|::.||....:....|..:|.|:.:.|:.|..:
 Worm  1052 YIVGLAHEANTEKAPVDLEAKFTPNILNTTVYIISMALQVCTFAVNYRGRPFMESLFENKAM--- 1113

  Fly  1318 FIVNLCIIVYLVLYPSDWVASF-----------FQLIVPPTMRFRYVMLAYGAASFICHI 1366
                    :|.:::....|.:.           |:|:|.|......:::...|...||:|
 Worm  1114 --------LYSIMFSGGAVFTLASGQATDLMIQFELVVLPEALRNALLMCVTADLVICYI 1165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
anne	NP_001096849.1	P5-ATPase	158..291	CDD:289194	22/139 (16%)
		P-ATPase-V	173..1355	CDD:273738	315/1336 (24%)
		E1-E2_ATPase	381..621	CDD:278548	76/262 (29%)
		Cation_ATPase	<758..813	CDD:289987	17/58 (29%)
		HAD_like	<1087..1137	CDD:304363	26/140 (19%)
catp-8	NP_502165.2	P-ATPase-V	37..1153	CDD:273738	317/1346 (24%)
		E1-E2_ATPase	251..>380	CDD:278548	47/137 (34%)
		Cation_ATPase	532..613	CDD:289987	30/128 (23%)
		COG4087	<793..>842	CDD:226572	23/48 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54176
OrthoDB	1	1.010	-	-		D172453at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930