DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18789 and amo1

DIOPT Version :9

Sequence 1:	NP_723704.1	Gene:	CG18789 / 317813	FlyBaseID:	FBgn0042127	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_596250.1	Gene:	amo1 / 2539911	PomBaseID:	SPBC15D4.10c	Length:	475	Species:	Schizosaccharomyces pombe

Alignment Length:	519	Identity:	120/519 - (23%)
Similarity:	183/519 - (35%)	Gaps:	165/519 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVVCRFFQQGSCRYGAKCNNEH---------FD---------------VKQYLK-ADMESSL--- 37
            ||||::|.|..||||..|.|:|         |.               |::.|| :|:::.|
pombe     1 MVVCKYFLQNRCRYGTNCKNQHTVPSNGQNAFSKVNVFRPENGRPPIWVQRRLKRSDLDNLLPNR 65

  Fly    38 ----------NGK-MWPLSAYGPFKDKANFPNFIQ-DQSFEEVRFMCYEAKRQNQFEQFSQQFNR 90
                      |.| .||.:.|...:   |.|:..: |.|.||:|:..|:||..|..:.:.|: .:
pombe    66 RMKDINDDLKNAKPQWPFTGYSVVE---NLPSIYEGDVSPEELRWWAYQAKATNNMQAYEQR-QK 126

  Fly    91 EVLEANNKMKTMLQMSPQVL--EMMIKIHETPEGGT--VSAAPQQSSNPFAAAAPAAANTSASIF 151
            ::::........::.||...  ||..|:    .|.|  .|...:.:||         :..:::.|
pombe   127 QLMDDVEAKAAAVKRSPAAAFDEMRNKL----VGKTNYKSIFDKSTSN---------STVTSNQF 178

  Fly   152 GKPTL-SAGNIFGNATSQASNTNSIFGGTISNANARNSIFGVGAAATGAQSVFGQPQQQQLQPAA 215
            .|||. |..|.|.|      |.||     .:|....|.|||....:.....:...|..|  ..::
pombe   179 NKPTQNSPFNSFSN------NNNS-----FNNNQQANDIFGAPTTSAFTSQLNASPFSQ--NTSS 230

  Fly   216 QAFQGGNIFAQAQVQVQAQPVN------------PNPFGGFQQQQQQPQSTGI-FGQAASQNMGG 267
            .:|.|.|       .||..|.:            |:.|||.    .||.|:.: .||....:...
pombe   231 NSFTGSN-------PVQNNPSSFGSSSFGSATSGPSAFGGI----SQPNSSFVNSGQGIPNSSFS 284

  Fly   268 MFTQASQQLQQQQQA-AASGLFAQAAASAFPNQQQMQQQ--QQMQQQQQMQQQQMHQQQQMQQQQ 329
            .|:|.:....|.|.. ..|.:|....||.|..|.|.||.  |.:..|..:..   :.|.......
pombe   285 SFSQVASGFSQSQNVNDPSSIFGPTVASGFGIQNQPQQSAFQNLNTQFSLPN---NSQPVFGHTS 346

  Fly   330 MQQ--QQQQFQMQQQQQMMQQQQQQAQP------------TNEIQSSVYS--------------- 365
            :.|  ....|.:|.....|||.|....|            |::|.:|.:|
pombe   347 LTQPVNPNGFTVQPPATFMQQPQGPFVPPNTTFESPFANVTSKISASGFSNDNPANKNIIQTPMF 411

  Fly   366 -------------------------RMEDLNE------QEIEAFKADQFLPGALPFKPPPRNFC 398
                                     .|.:.|:      :.|:.|:|..|:||.:|...||..||
pombe   412 GSSNTIDGPINPIGASSIQTLDDQVEMSNSNQNLAFPPEMIQQFEAQDFIPGKVPTTAPPPQFC 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18789	NP_723704.1	ZnF_C3H1	1..22	CDD:214632	12/20 (60%)
CG18789	NP_723704.1	Nucleoporin_FG	145..>204	CDD:290362	16/59 (27%)
amo1	NP_596250.1	ZnF_C3H1	1..22	CDD:214632	12/20 (60%)
amo1	NP_596250.1	YTH1	139..453	CDD:227416	73/353 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I1952
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47178
orthoMCL	1	0.900	-	-		OOG6_110455
Panther	1	1.100	-	-	LDO	PTHR46527
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4413
TreeFam	0	0.000	Not matched by this tool.
	6	5.960