| Sequence 1: | NP_112420.1 | Gene: | HNRNPA1 / 3178 | HGNCID: | 5031 | Length: | 372 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_014224.2 | Gene: | NOP13 / 855547 | SGDID: | S000005119 | Length: | 403 | Species: | Saccharomyces cerevisiae |
| Alignment Length: | 244 | Identity: | 59/244 - (24%) |
|---|---|---|---|
| Similarity: | 102/244 - (41%) | Gaps: | 45/244 - (18%) |
- Green bases have known domain annotations that are detailed below.
|
Human 8 KEPEQLRKLFIGGLSFETTDESLRSHF--------EQWGTLTD---------CVVMRDPNTKRSR 55
Human 56 GFGFVTYATVEEVDAAMNARPHKVDGR---VVEPKRAVSRED-------SQRPGAHLTVKKIFVG 110
Human 111 GIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHD---------SVDKIVIQK 166
Human 167 YHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDN 215 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HNRNPA1 | NP_112420.1 | Globular A domain | 4..94 | 22/105 (21%) | |
| RRM1_hnRNPA1 | 12..92 | CDD:410154 | 19/99 (19%) | ||
| Globular B domain | 95..185 | 27/98 (28%) | |||
| RRM2_hnRNPA3 | 105..184 | CDD:409996 | 24/87 (28%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 182..216 | 10/34 (29%) | |||
| RNA-binding RGG-box | 218..240 | ||||
| HnRNPA1 | 312..344 | CDD:463312 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 317..372 | ||||
| Nuclear targeting sequence (M9) | 320..357 | ||||
| NOP13 | NP_014224.2 | RRM1_Nop13p_fungi | 127..217 | CDD:409830 | 19/89 (21%) |
| RRM2_Nop13p_fungi | 241..316 | CDD:409831 | 22/74 (30%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||