| Sequence 1: | NP_112420.1 | Gene: | HNRNPA1 / 3178 | HGNCID: | 5031 | Length: | 372 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_523957.1 | Gene: | lark / 38811 | FlyBaseID: | FBgn0011640 | Length: | 352 | Species: | Drosophila melanogaster |
| Alignment Length: | 219 | Identity: | 62/219 - (28%) |
|---|---|---|---|
| Similarity: | 96/219 - (43%) | Gaps: | 44/219 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Human 15 KLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEE-VDAAMNARPHK 78
Human 79 VDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSG 143
Human 144 KKRGFAFVTFD-DHDSVDKIVIQKYHTVNGHNCEVRKALS----KQEMASASSSQR-GRSGS--- 199
Human 200 ------GNFGGGR-------GGGF 210 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HNRNPA1 | NP_112420.1 | Globular A domain | 4..94 | 25/79 (32%) | |
| RRM1_hnRNPA1 | 12..92 | CDD:410154 | 23/77 (30%) | ||
| Globular B domain | 95..185 | 24/94 (26%) | |||
| RRM2_hnRNPA3 | 105..184 | CDD:409996 | 22/83 (27%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 182..216 | 15/50 (30%) | |||
| RNA-binding RGG-box | 218..240 | ||||
| HnRNPA1 | 312..344 | CDD:463312 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 317..372 | ||||
| Nuclear targeting sequence (M9) | 320..357 | ||||
| lark | NP_523957.1 | RRM1_2_CoAA_like | 8..73 | CDD:409779 | 22/72 (31%) |
| RRM1_2_CoAA_like | 87..152 | CDD:409779 | 20/72 (28%) | ||
| hnRNP-R-Q | <88..>258 | CDD:273732 | 35/126 (28%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||