DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15347 and CG13492

DIOPT Version :9

Sequence 1:	NP_001188562.1	Gene:	CG15347 / 31779	FlyBaseID:	FBgn0030040	Length:	229	Species:	Drosophila melanogaster
Sequence 2:	NP_726121.3	Gene:	CG13492 / 37487	FlyBaseID:	FBgn0034662	Length:	2979	Species:	Drosophila melanogaster

Alignment Length:	237	Identity:	60/237 - (25%)
Similarity:	105/237 - (44%)	Gaps:	47/237 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ISCGMTQSKRSVPLAQFADG----------------------CIQCNSKDNERCATDPLSLLNR- 58
            :.|..:|::.|  |.|:.:|                      |:.|:|.....||.||.::|..
  Fly  2759 MGCASSQNESS--LEQWQEGNLLYSCQGSECNELSRLPTEGECLSCDSSKTLECAQDPTAVLTTI 2821

  Fly    59 NCSDGSSNCYSRVLDGYTIRGCAVDLDNATRNSCNNELLCQLCTYSEGCNRNTFPLSRLMCLQCT 123
            .|...:|:|.:|:.:|:|.|||..::.:...:||..:..|..|:.:: ||...||.:|..|..|
  Fly  2822 TCHAPNSDCITRLENGHTHRGCRSEVSSTESSSCVADGTCSACSGAK-CNVEIFPNNRRRCYIC- 2884

  Fly   124 GNSTSSSCATETYVSAKICPLYKFGDKCYIRNSNRTVDGSFQRGCLTSANARKQCVKDG--NCYT 186
             ||.......:...|..:||:|...|:|....:|    |..:|||.:..    :|..|.  :|..
  Fly  2885 -NSIDDPLCAQHPSSLAVCPIYAANDECVTSLNN----GLLRRGCASEL----ECEIDNEDHCNK 2940

  Fly   187 CEGRGCNFLLANDTNIPLARDSG--AQLIISMTLLISGLVAA 226
            |...|||       .|.|...:|  :.:.:.:||:::.|:::
  Fly  2941 CSTDGCN-------TIELTGSAGGLSGMGLGLTLIVAWLISS 2975

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15347	NP_001188562.1	DUF753	39..189	CDD:283175	44/152 (29%)
CG13492	NP_726121.3	DUF753	112..263	CDD:283175
		DUF753	281..428	CDD:283175
		DUF753	368..520	CDD:283175
		DUF753	537..674	CDD:283175
		DUF753	700..844	CDD:283175
		DUF753	871..>965	CDD:283175
		DUF753	956..1104	CDD:283175
		DUF753	1122..1266	CDD:283175
		DUF753	1206..1336	CDD:283175
		DUF753	1376..1523	CDD:283175
		DUF753	1540..1690	CDD:283175
		DUF753	1721..>1811	CDD:283175
		DUF753	1797..1948	CDD:283175
		DUF753	1966..2110	CDD:283175
		DUF753	2051..2191	CDD:283175
		DUF753	2220..2368	CDD:283175
		DUF753	2384..2530	CDD:283175
		DUF753	2640..2769	CDD:283175	2/9 (22%)
		DUF753	2801..2943	CDD:283175	44/152 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455219
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2F712
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D25716at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21721
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850