Protein Alignment org-1 and EOMES

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001265111.1
• Gene: EOMES / 8320
• HGNCID: 3372
• Length: 705
• Species: Homo sapiens
• Alignment Length: 508
• Identity: 156/508 - (30%)
• Similarity: 210/508 - (41%)
• Gaps: 122/508 - (24%)

  Fly    71 EQIDAKLADIETHSTGSTGTAN-SNSSTSS----ISNPS---------C---PDQSSSSSSSSVS 118
            |::.:..|.....:..:..||. |..|.||    :.:|.         |   |.|:::.:.....
Human   112 EELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPV 176

  Fly   119 LPTDYAGVHSEASMAPTAG--------GTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVK 175
            .|......:...||.|..|        |.|.....||..|.:..|              ..|...
Human   177 YPAPNGARYPYGSMLPPGGFPAAVCPPGRAQFGPGAGAGSGAGGS--------------SGGGGG 227

  Fly   176 PNSHNISKGESEPV---HPSLA------------------QAIVVLETKALWDQFHAQGTEMIIT 219
            |.::..|:|  .|:   :|..|                  :|.|.|..:.||.:||...||||||
Human   228 PGTYQYSQG--APLYGPYPGAAAAGSCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIIT 290

  Fly   220 KTGRRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKAD-PISPPRIHVHP 283
            |.||||||.....|.||:|.|.|...::.|..|...:|  |....||..|||| .:...:::|||
Human   291 KQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR--FQGGKWVTCGKADNNMQGNKMYVHP 353

  Fly   284 DSPAVGSNWMKQIVSFDKLKLTNNQLDENGH---IILNSMHRYQPRFHLVYLPPKNASLDENEHS 345
            :||..||:||:|.:||.|||||||:...|.:   |:|.|:|:||||.|:|.:...... |.|| .
Human   354 ESPNTGSHWMRQEISFGKLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVE-DLNE-P 416

  Fly   346 SHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDD-------GTND------------- 390
            |..:||.|.||.|.|||||||..:|||||..|||||||||:       ..||
Human   417 SKTQTFTFSETQFIAVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSH 481

  Fly   391 -VTTGGGSSMSSMSHE------SQARMKQQQQQQQQQQQQLQQQQQQQQQLKERTAATSNFGLSC 448
             :..||...:.|...|      .|||....::...|....|..||.:
Human   482 QIVPGGRYGVQSFFPEPFVNTLPQARYYNGERTVPQTNGLLSPQQSE------------------ 528

  Fly   449 SELAIEQQQ---QQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQ-QLQQQH 497
             |:|...|:   ...||.|..:|..  ||..:...|..||.|.::. .||..|
Human   529 -EVANPPQRWLVTPVQQPGTNKLDI--SSYESEYTSSTLLPYGIKSLPLQTSH 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	97/204 (48%)
EOMES	NP_001265111.1	TBOX	267..460	CDD:238106	97/196 (49%)
		T-box_assoc	482..703	CDD:292794	27/118 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910