Protein Alignment org-1 and TBX15

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: XP_005271218.1
• Gene: TBX15 / 6913
• HGNCID: 11594
• Length: 635
• Species: Homo sapiens
• Alignment Length: 696
• Identity: 206/696 - (29%)
• Similarity: 299/696 - (42%)
• Gaps: 163/696 - (23%)

  Fly    53 IEACIQTAGKDRSSYKPLEQIDAKLADIETHSTGSTGTANSNSSTSSISNPSCPDQSSSSSSSSV 117
            :||.|.:..|     :.|...:.|..|:...:....|........::......||...|:.|.|.
Human    20 VEALIGSNKK-----RKLRDWEEKGLDLSMEALSPAGPLGDTEDAAAHGLEPHPDSEQSTGSDSE 79

  Fly   118 SLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVKPNSHNIS 182
            .|        :|.:....:..|.:.:.:||.|.|:.:
Human    80 VL--------TERTSCSFSTHTDLASGAAGPVPAAMS---------------------------- 108

  Fly   183 KGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMD 247
                     |:.:..|.|:...||.:||..||||||||.||||||..:|:|.|||||..|...||
Human   109 ---------SMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMD 164

  Fly   248 FVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDEN 312
            .||:|:|||||.:|:|.|:|||.||...|||:::||||.|.|..||:|:|||||||||||:||:.
Human   165 IVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQ 229

  Fly   313 GHIILNSMHRYQPRFHLV-------YLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVT 370
            |||||:|||:||||.|::       ..|.|...:.:.     .:||.||||.||.|||||||::|
Human   230 GHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDG-----VKTFNFPETVFTTVTAYQNQQIT 289

  Fly   371 QLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSH-ESQARMKQQQQQQQQQQQQLQQQQQQQQQL 434
            :|||..|||||||||.|.|  .||..:.|.:.:. ....|....:.....|:||..::..|...:
Human   290 RLKIDRNPFAKGFRDSGRN--RTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQASKKTSQGYTV 352

  Fly   435 KERTAATSNFGLSCSELAIEQQQQQ---QQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQQ 496
            .:.::.|.         |||..:::   .:::|  ....:|::|||...||
Human   353 NQHSSETD---------AIELYERRVWLMERRG--STGTSPTTSSTGTPSP-------------- 392

  Fly   497 HQQQQQQQHQSQQQHLHQQ-------HQA-NQQQSLLQQSQ----NHTQYGSYHHAYQAQVQSHP 549
                      |...||...       |.| |......::||    |.:.|.....:..|.:||:|
Human   393 ----------SASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYP 447

  Fly   550 ---------LTPHSSSSASPPATAAPGASAA-------TAAVAGGAGAAGAGG-----ATSATQ- 592
                     |...::|:..|..|..|..:.:       ..::.|.:.....||     .||..|
Human   448 GLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQY 512

  Fly   593 VMSAANIYSSIGQPYA-----QEQSNFGAIYHHNAAAAAAAHYHHGHAHGHAHSHAHAHAHGPYA 652
            ||.|.|..||...|:.     .:||::.|...||..          :.:|:....:...|..|
Human   513 VMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPY----------NLYGYNFPTSPRLAASP-- 565

  Fly   653 SAYDKLKVSRHA------AAAAYGMGATYPSFYGSAAHHQMMRPNS 692
               :||..|:..      :..|:|.....||....:.|.....||:
Human   566 ---EKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNN 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	115/200 (58%)
TBX15	XP_005271218.1	TBOX	113..308	CDD:238106	115/199 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940