Protein Alignment org-1 and TBX6

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_004599.2
• Gene: TBX6 / 6911
• HGNCID: 11605
• Length: 436
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 142/419 - (33%)
• Similarity: 205/419 - (48%)
• Gaps: 103/419 - (24%)

  Fly   186 SEPVHPSLAQAI-------VVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYI 243
            :||. ||..:|:       :.||.:.||.:|.:.||||||||.||||||..:|.:.||||.|.|:
Human    75 TEPA-PSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYL 138

  Fly   244 CMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQ 308
            .::|.:|:|..|||:  ....|..:|||:|..|.|:::||||||.|::||:|.|||.::||||:.
Human   139 FLLDVIPVDGARYRW--QGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNST 201

  Fly   309 LDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLK 373
            ||.:||:||:|||:||||.|||    :.|.|. ::|.....:|.||||:|.:||||||.::||||
Human   202 LDPHGHLILHSMHKYQPRIHLV----RAAQLC-SQHWGGMASFRFPETTFISVTAYQNPQITQLK 261

  Fly   374 ISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQLKERT 438
            |::||||||||::|.|            ...|..||:|::.:..:                   .
Human   262 IAANPFAKGFRENGRN------------CKRERDARVKRKLRGPE-------------------P 295

  Fly   439 AATSNFGLS------C-SELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQQ 496
            |||..:|..      | |.|..:.::...:|       |.....:|:..:|...|...|..|
Human   296 AATEAYGSGDTPGGPCDSTLGGDIRESDPEQ-------APAPGEATAAPAPLCGGPSAEAYL--- 350

  Fly   497 HQQQQQQQHQSQQQHLHQQHQANQQQSLLQQSQNHTQYGSYHHAYQAQVQSHPLTPHSSSSASPP 561
                           ||.                    .::|.|     .||..|...|...:|.
Human   351 ---------------LHP--------------------AAFHGA-----PSHLPTRSPSFPEAPD 375

  Fly   562 ATAAPGASAATAAVAGGAGAAGAGGATSA 590
            :..:...|||...:..|:|.:|...|..|
Human   376 SGRSAPYSAAFLELPHGSGGSGYPAAPPA 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	102/200 (51%)
TBX6	NP_004599.2	TBOX	90..277	CDD:238106	101/193 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..339		18/105 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	360..379		5/18 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910