Protein Alignment org-1 and tbx20

DIOPT Version :10

• Sequence 1: NP_511085.2
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001030292.1
• Gene: tbx20 / 619590
• XenbaseID: XB-GENE-487334
• Length: 440
• Species: Xenopus tropicalis
• Alignment Length: 575
• Identity: 191/575 - (33%)
• Similarity: 248/575 - (43%)
• Gaps: 204/575 - (35%)

  Fly    48 SPMKQIE--------ACIQTAG--KDR----SSYKPLEQIDAKLADIETHSTGSTGTANSNSSTS 98
            ||..|:.        |.:.::|  ||:    |:.|||||...|                     |
 Frog     6 SPKPQLSSRANAFSIAALMSSGTPKDKETQESTIKPLEQFVEK---------------------S 49

  Fly    99 SISNP----SCPDQSSSSSSSSVSLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFK 159
            |.|.|    |..|.....::|..||.|:        .:.||.
 Frog    50 SCSQPLGDISIVDSHGEFTNSPSSLCTE--------PLIPTT----------------------- 83

  Fly   160 GQHKKDNNSAENGTVKPNSHNISKGESEPVHPS--LAQAIVVLETKALWDQFHAQGTEMIITKTG 222
                                        ||.||  :|:....||||.|||:||..||||||||:|
 Frog    84 ----------------------------PVIPSEEMAKISCSLETKELWDKFHDLGTEMIITKSG 120

  Fly   223 RRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPA 287
            ||||||.:|...|:|..|.||.:||.||:|:||||||:|.|.|:|||||||..|.|::||||||.
 Frog   121 RRMFPTIRVSFSGVDADAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPF 185

  Fly   288 VGSNWMKQIVSFDKLKLTNNQLDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFI 352
            .|...:||:|||:|:|||||:||::|||||||||:||||.|::......||| .|..|..|||||
 Frog   186 TGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASL-LNLKSEEFRTFI 249

  Fly   353 FPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQ 417
            |.||.||||||||||.:|:|||.||||||||||          .|.::.:..||...:.|:....
 Frog   250 FQETVFTAVTAYQNQLITKLKIDSNPFAKGFRD----------SSRLTDIERESVESLIQKHSYA 304

  Fly   418 Q-------------QQQQQLQQQ-----QQQQQQLKERTAATSNF------------GLSCSELA 452
            :             :..|.:|.:     ..:...|....::||.|            |.|.:.||
 Frog   305 RSPIRTYGDEDVLGEDGQTMQSRGSAFTTSENLSLSSWVSSTSGFSGFQHPQSLTALGTSTASLA 369

  Fly   453 IEQQQQQQQQQGVLQ------LPATPS--SSSTSGNSPDLLGYQMEQQLQQQHQQQQQQQHQSQQ 509
               .......||.|.      :|.|||  :||..|:.|....:.|.:
 Frog   370 ---TPIPHPIQGTLPPYSRLGMPITPSALASSMQGSGPTFPSFHMPR------------------ 413

  Fly   510 QHLHQQHQANQQQSLLQQSQNHTQYGSYHHAYQ----AQVQSHPLTPHSSSSASP 560
                                       |||.:|    |.:|.   ..|||:..:|
 Frog   414 ---------------------------YHHYFQQGPYAAIQG---LRHSSAVMTP 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_511085.2	T-box_TBX1_10-like	195..385	CDD:410313	122/189 (65%)
tbx20	NP_001030292.1	T-box_TBX20-like	94..283	CDD:410319	124/199 (62%)
		T-box	98..282		122/184 (66%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<314..>402	CDD:476819	19/90 (21%)