Protein Alignment org-1 and tbx2

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001030291.1
• Gene: tbx2 / 619588
• XenbaseID: XB-GENE-1018115
• Length: 685
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 188/576 - (32%)
• Similarity: 267/576 - (46%)
• Gaps: 130/576 - (22%)

  Fly   131 SMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVKPNSHNISKGESEPVHPSLAQ 195
            ::.|.|.|..::..|..|.:.:.......|.|.:..:.....:::|.    .:.|.:|.
 Frog    42 TLPPAALGKPLSDPSLAGAAEAGLHVSALGHHHQAAHLRSLKSLEPE----EEVEDDPK------ 96

  Fly   196 AIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAF 260
              |.||.|.||||||..||||:|||:||||||.|:||:.|||..|.||.:||.|..||.||:  |
 Frog    97 --VTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYK--F 157

  Fly   261 HNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDENGHIILNSMHRYQP 325
            |||.|:|||||||..|.|:::||||||.|..||.:.|:|.|||||||..|::|..||||||:|||
 Frog   158 HNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQP 222

  Fly   326 RFHLV------YLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFR 384
            |||:|      .||           .|.|||::||||.|.|||||||.::|||||.:||||||||
 Frog   223 RFHIVRANDILKLP-----------YSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFR 276

  Fly   385 DDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQLK-ERTAATSNFGLSC 448
            |       ||.|                  ::::::|..|...:..::|.| :|..|.|: ..||
 Frog   277 D-------TGNG------------------RREKRKQLSLPSLRMYEEQCKADRDGAESD-ASSC 315

  Fly   449 -----------------SELAIEQQQQQQQ------QQGVLQLPATPSSSSTSG-----NSPDLL 485
                             |.|.:.:..::::      |:...:...|..|.|..|     :||.|.
 Frog   316 DPAPGRDSLHSPLSTEPSPLRLHRSNREEKFGADSDQELDRREVRTARSHSPVGHRSPPSSPRLE 380

  Fly   486 GYQMEQQLQQQHQQQQQQQHQSQQQHLHQQHQANQQQSLLQQ-SQNHTQYGSYHHAYQA--QVQS 547
            ....::...::..:..:.:.........:..:.::.:|..:: |::..:.||......|  .||:
 Frog   381 DRGKDKNTPEKKSESPESRKDGGDNVFSRSLEKDKGESRRKEDSKSDPECGSLSKETFAPLMVQT 445

  Fly   548 HPLTPHSSSS--------------------ASPPA-------TAAPGASAATA-----AVAGGAG 580
            .. .||.|:|                    |:.|.       |..|||.:|..     |...||.
 Frog   446 DS-PPHLSASHLQSLALSGLHGQQFFNPLNAAQPLFIHPGQFTMGPGAFSAMGMGHLLASMTGAS 509

  Fly   581 AAGAGGATSATQVMSAANIYSSIGQPYAQEQS----NFGAI----YHHNAAAAAAA 628
            |...|..:|......||.....:.|.....|.    .||.:    |.:.|||||||
 Frog   510 ALDNGSLSSVQGATGAATFPFHLSQHMLASQGIPMPAFGGLFPYPYTYMAAAAAAA 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	118/199 (59%)
tbx2	NP_001030291.1	T-box	97..277	CDD:366363	116/192 (60%)
		T-box	99..277		115/190 (61%)
		TBX	295..370	CDD:372213	13/75 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	606..660

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940