Protein Alignment org-1 and tbr1b

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001108562.1
• Gene: tbr1b / 58042
• ZFINID: ZDB-GENE-000323-1
• Length: 676
• Species: Danio rerio
• Alignment Length: 651
• Identity: 179/651 - (27%)
• Similarity: 256/651 - (39%)
• Gaps: 145/651 - (22%)

  Fly    52 QIEACIQTA-GKDR------SSYKPLEQIDAKLADIETHSTGSTGTANS--NSSTSSISNPSCPD 107
            |:|.||..| .:.:      |.|...:..:..|.|....|.|.....:|  ..:::.::|.|..|
Zfish     2 QLERCISPALARSKKCMIVGSGYPNAQASELALQDYPIISIGDNLERSSPLKKNSAGMTNQSEAD 66

  Fly   108 QSSSSSSSS-----VSLPTDYAGV----H------------SEASMAPTAGGTAVTTTSAGG--- 148
            ..:.|..||     ..|..|..||    |            |::|....:..|.....|..|
Zfish    67 NFADSKDSSGDVQRGKLSPDLDGVADSRHTFDGSAGERYLLSQSSQVQPSPTTMFPYPSQHGPTH 131

  Fly   149 VSASTAS-KKFKGQHKKDNNSAENGTVKPNSHNISKGESEPVHP-----------------SLAQ 195
            .:.|.|| .::...|....|.|.|..:   |::..:|.:...:|                 |.||
Zfish   132 PAFSIASPSRYMAHHPVITNGAYNSLL---SNSSPQGYATAGYPYAQQYGHAYQGTAFYQFSSAQ 193

  Fly   196 AIVV-------LETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMDFVPMDD 253
            |.:|       |..:|||.:||...|||||||.||||||.....|.||||.|.|...:|.:..|.
Zfish   194 AGLVPGKAQVYLCNRALWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADP 258

  Fly   254 KRYRYAFHNSCWVVAGKADP-ISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDENG---H 314
            ..:|  |....||..||||. ::..|:::|||||..|::||:|.:||.|||||||:...|.   .
Zfish   259 NHWR--FQGGKWVPCGKADTNVTGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGATNNTGQM 321

  Fly   315 IILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPF 379
            ::|.|:|:||||.|:|.:  .....::.......:||.||||.|.|||||||..:|||||..|||
Zfish   322 VVLQSLHKYQPRLHVVQV--NEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPF 384

  Fly   380 AKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQLKERTAATSNF 444
            ||||||: .:.|.||......:.|.....|                    .|.....|.|.|.:|
Zfish   385 AKGFRDN-YDTVYTGCDIDRLTPSPGDSPR--------------------SQIMPSARYAMTGSF 428

  Fly   445 GLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGN--SPDLLGYQMEQQLQQQHQQQQQQQHQS 507
               ..:..:....:.:...||...|.|..|...|.:  ||
Zfish   429 ---LQDQFVSSYAKSRFHPGVGGAPGTDRSVPLSNSLLSP------------------------- 465

  Fly   508 QQQHLHQQHQANQQQSLLQQSQNHTQY--GSYHHAYQAQVQSHPLTPHSSSSASPPATAAPGASA 570
              |...:...|:.|:..:..:.|...:  .:|..|..|....:..|..|.::|...|...|||..
Zfish   466 --QQTEETTVASPQRWFVTPANNRLDFAASAYDAAAAADFAGNAATLLSYAAAGVKALPLPGAGC 528

  Fly   571 ATAAVAGGAGAAGAGGATSATQVMSAANIYS-----SI----------------GQPYAQEQSNF 614
            :...:.......|.|..|.......::::.|     |:                |.|.|.|:|..
Zfish   529 SNRPLGYYGEPPGWGTRTPPQYCSKSSSVLSCWPSNSVGSRTTASSYLVPGLEDGDPIAPERSPL 593

  Fly   615 G 615
            |
Zfish   594 G 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	96/204 (47%)
tbr1b	NP_001108562.1	TBOX	200..393	CDD:238106	93/197 (47%)
		T-box_assoc	415..673	CDD:292794	38/210 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910