Protein Alignment org-1 and tbx18

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_705951.1
• Gene: tbx18 / 572713
• ZFINID: ZDB-GENE-020529-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 627
• Identity: 188/627 - (29%)
• Similarity: 248/627 - (39%)
• Gaps: 188/627 - (29%)

  Fly    53 IEACIQTAGK----DRSSYKPLEQID--AKLADIETHSTGSTGTANSNSSTSSISNPSCPDQSSS 111
            :||.|.|..|    :..|....|:|:  .::.:....|||.|                ||    |
Zfish    20 VEALIGTEKKRKLEEEDSENCFEEINEVPRMTESPQPSTGRT----------------CP----S 64

  Fly   112 SSSSSVSLPTDYAGVHSEA---SMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGT 173
            :.|..:...:|.:....:.   |..|.:.|..|...||
Zfish    65 TRSCEIDCTSDESPEPEDVLLDSPQPASQGAQVLVQSA--------------------------- 102

  Fly   174 VKPNSHNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDP 238
                   .|.||         :..|.|:...||.:||..||||||||.||||||..:|:|.||||
Zfish   103 -------TSSGE---------EMRVDLQGSDLWKRFHEIGTEMIITKAGRRMFPAMRVKIAGLDP 151

  Fly   239 HATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLK 303
            |..|...||.||:|:|||||.:|:|.|:|||.||...|||:::||||||.|..||:|::||||||
Zfish   152 HQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLK 216

  Fly   304 LTNNQLDENGHIILNSMHRYQPRFHLV------YLPPKNASLDENEHSSHFRTFIFPETSFTAVT 362
            ||||:||:.|||||:|||:||||.|::      .|.|..|.    ......:.|.|.||.||.||
Zfish   217 LTNNELDDQGHIILHSMHKYQPRVHVIRKECGEELSPVKAV----PTGDGVKAFSFTETVFTTVT 277

  Fly   363 AYQNQRVTQLKISSNPFAKGFRDDGTN---------------------------DVTTGGGSSMS 400
            |||||::|:|||..|||||||||.|.|                           .:|..|.:.
Zfish   278 AYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDILGITKQGAAG-- 340

  Fly   401 SMSH---ESQARMKQQQQQQQQQQQQLQQQQQQQQQLKERTAATSNFGLS------CSELAIEQQ 456
              ||   .|.|.:                       |...:..:..|.|.      |......:.
Zfish   341 --SHGVVGSSAHL-----------------------LSSSSCPSPTFHLGSGAGPVCDYSTCSRT 380

  Fly   457 QQQQQQQGV---------LQLPATPSSSSTSGNSPDLLGYQMEQ----------QLQQQHQQQQQ 502
            .....:.|.         |..| |..:.|||.:|..:.|.:.|.          |:........|
Zfish   381 SHPLHRYGPSLSADSYSRLTSP-TADAFSTSRSSTYVSGTESEAFSCTQTGLPIQIHSMPSTTSQ 444

  Fly   503 QQHQSQQQHLHQQHQANQQQSLLQQSQN----HTQYGSYHHAYQAQVQSHPLTPHSSSSASPPAT 563
            .|: ....|.|.....||.   .|.|.|    |..||.|.:.:               |.||...
Zfish   445 LQY-LMPGHAHNAFSTNQS---TQGSYNGFRLHNPYGLYGYNF---------------STSPRLA 490

  Fly   564 AAPGASAATAAVAGGAGAAGAGGATSATQVMSAANIYSSIGQ 605
            .:|..:|||.....|:..:|..........|...::.||..|
Zfish   491 TSPEKAAATQTSFLGSSPSGTLTDRQVLSTMDGLHMLSSSQQ 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	114/199 (57%)
tbx18	NP_705951.1	TBOX	109..304	CDD:238106	114/198 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593600
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.970