Protein Alignment org-1 and TBX22

DIOPT Version :10

• Sequence 1: NP_511085.2
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_058650.1
• Gene: TBX22 / 50945
• HGNCID: 11600
• Length: 520
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 156/475 - (32%)
• Similarity: 214/475 - (45%)
• Gaps: 128/475 - (26%)

  Fly   150 SASTASKKFKGQHKKD-NNSAENGTVKPNSHNISKGESEPVHPSLAQAIVVLETKA--LWDQFHA 211
            ||:..|:..:.|.|.: :.||.:|....:.:..|   ||    ||.:..:.:|.:.  ||.:||.
Human    50 SAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNS---SE----SLEEKDIQMELQGSELWKRFHD 107

  Fly   212 QGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPIS- 275
            .||||||||.||||||:.:|::.||||...|...:|.||:|.|||||.:|:|.|:|||..|.:.
Human   108 IGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCI 172

  Fly   276 PPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDENGHIILNSMHRYQPRFHLVYLPPKNASLD 340
            .||.:||||||..|..||:||:|||::|||||::|:.|||||.|||:|:||.|::   .:.:|:|
Human   173 IPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVI---EQGSSVD 234

  Fly   341 ENEHSS----HFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTN------------ 389
            .::..|    ..:||.|.||.||.|||||||::|:|||..|||||||||.|.|
Human   235 LSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYP 299

  Fly   390 ------------------------DVTTGGGS-----------SMSSMSHESQARMKQQQQQQQQ 419
                                    .||:.||:           ..|.|.|
Human   300 WRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFH--------------- 349

  Fly   420 QQQQLQQQQQQQQQLKERTAATSNFGLSCSE---------LAIEQQQQQQQQQGVLQLPATPSSS 475
                               ..||:.|:.|.|         |..:.......||..|.||| |...
Human   350 -------------------LPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPA-PERL 394

  Fly   476 STSGNSPDLLGYQMEQQLQQQ---HQQQQQQQHQSQQQHLHQQHQANQQQSLLQQSQN------- 530
            ::|.:|..|....||..:...   ...:......|..|:|...:..||....||...|
Human   395 ASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSI 459

  Fly   531 ---------HTQYGSYHHAY 541
                     |..|..|.:.:
Human   460 TPEALSCSFHPSYDFYRYNF 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_511085.2	T-box_TBX1_10-like	195..385	CDD:410313	103/196 (53%)
TBX22	NP_058650.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..91		13/47 (28%)
		T-box_TBX22-like	90..283	CDD:410326	103/195 (53%)