Protein Alignment org-1 and Tbx3

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_853669.1
• Gene: Tbx3 / 353305
• RGDID: 735203
• Length: 743
• Species: Rattus norvegicus
• Alignment Length: 680
• Identity: 207/680 - (30%)
• Similarity: 285/680 - (41%)
• Gaps: 160/680 - (23%)

  Fly    97 TSSISNPSCPDQSSSSSSSSVSLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFKGQ 161
            ||...:|..|.::...:.|:|   ..:......|...|..|..|:   |..|..|.....:..|
  Rat    13 TSMAYHPFLPHRAPDFAMSAV---LGHQPPFFPALTLPPNGAAAL---SLPGALAKPIMDQLVG- 70

  Fly   162 HKKDNNSAENG----TVKPNSHNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTG 222
                  :||.|    ::.|.:|.......||.........|.||.|.||||||.:||||:|||:|
  Rat    71 ------AAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKSG 129

  Fly   223 RRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPA 287
            |||||.|:||..|||..|.||.:||.:..||.||:  ||||.|:|||||||..|.|:::||||||
  Rat   130 RRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPA 192

  Fly   288 VGSNWMKQIVSFDKLKLTNNQLDENG--------------------HIILNSMHRYQPRFHLV-- 330
            .|..||.::|:|.|||||||..|::|                    ..||||||:||||||:|
  Rat   193 TGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA 257

  Fly   331 ----YLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTNDV 391
                .||           .|.|||::||||.|.|||||||.::|||||.:|||||||||.|
  Rat   258 NDILKLP-----------YSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTG---- 307

  Fly   392 TTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQ------QQQQQLKERTAATSNFGLSC-S 449
             .|.......::.:|.....::.:::.....:...:|      .|.......|..|||....| |
  Rat   308 -NGRREKRKQLTLQSMRVFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSNLKDLCPS 371

  Fly   450 ELAIEQQQQQQQQQGV--------------------------LQL-PATPS----------SSST 477
            |...:.:.:.:::.|.                          .|| ||.||          :|..
  Rat   372 EAESDAEAESKEEHGPEACDTAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPD 436

  Fly   478 SGNSPDLLGYQMEQQLQQQHQQQQQQQHQS---QQQHLHQQHQANQQQSLLQQSQNHTQYGSYHH 539
            |.:||..:..........:|:...::...|   .:........|....|:...:..|...|....
  Rat   437 SRHSPATISSSTRVPGADEHRSPGREGPVSAKVDEARALPAKDAFAPLSVQTDATAHLTQGPLPG 501

  Fly   540 -------AYQAQVQSHPLTPH----------SSSSA--SPPATAAPGASAA-----TAAVAGGAG 580
                   |.|.....|||..|          ||.:|  .|......|||..     :.|:|..|.
  Rat   502 LGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAA 566

  Fly   581 AAGAGGATSAT-------QVMSAANIYSSIGQPYAQEQSNFGAI----YHHNAAAAAAAHYHHGH 634
            |.|..||::||       .|:::..:          ..|.||::    |.:.||||||
  Rat   567 AQGLSGASAATLPFHLQQHVLASQGL----------AMSPFGSLFPYPYTYMAAAAAA------- 614

  Fly   635 AHGHAHSHAHAHAHGPYASAYDKLKVSRHA 664
            :...|.|..|.|......|...:|:.|.::
  Rat   615 SSAAASSSVHRHPFLNLNSMRPRLRYSPYS 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	118/219 (54%)
Tbx3	NP_853669.1	T-box_TBX2_3-like	101..305	CDD:410314	115/216 (53%)
		TBX	323..404	CDD:403708	10/80 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..467		14/95 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810