Protein Alignment org-1 and Tbx5

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_001009964.1
• Gene: Tbx5 / 304514
• RGDID: 1305702
• Length: 517
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 170/520 - (32%)
• Similarity: 235/520 - (45%)
• Gaps: 113/520 - (21%)

  Fly   182 SKGESEPVHPSLAQAI----VVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATY 242
            ||..|.|......|.:    |.|..:.||.:||..||||||||.||:|||:::|::.||:|...|
  Rat    36 SKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRQMFPSYKVKVTGLNPKTKY 100

  Fly   243 ICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNN 307
            |.:||.||.||.||::|  ::.|.|.|||:|..|.|::|||||||.|::||:|:|||.|||||||
  Rat   101 ILLMDIVPADDHRYKFA--DNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNN 163

  Fly   308 QLDENGHIILNSMHRYQPRFHLVYLPPKNASLDEN----EHSSHFRTFIFPETSFTAVTAYQNQR 368
            .||..|||||||||:||||.|:|       ..|||    ..::.|.|.:||||:|.|||:|||.:
  Rat   164 HLDPFGHIILNSMHKYQPRLHIV-------KADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHK 221

  Fly   369 VTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQ 433
            :|||||.:||||||||  |::|:.....|.|.|..:....|            ..::.:......
  Rat   222 ITQLKIENNPFAKGFR--GSDDLELHRMSRMRSKEYPVVPR------------STVRHKVANHSP 272

  Fly   434 LKERTAA---TSNFGLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQ 495
            ....|.|   :||.|           .|.|.:.||            ||.|.|||.......|.|
  Rat   273 FSSETRALSTSSNLG-----------SQYQCENGV------------SGPSQDLLPPPNPYPLAQ 314

  Fly   496 QHQQQQQQQHQSQQQHLHQQHQANQQQSLLQQSQNHTQYGSYHHAYQA-----QVQSHPLTPHSS 555
            :|.|......:..::....:|...:.......|:..|.|.|.:...|.     :.:|........
  Rat   315 EHSQIYHCTKRKDEECSSTEHPYKKPYMETSPSEEDTFYRSGYPQQQGLSTSYRTESAQRQACMY 379

  Fly   556 SSASPPA--------------TAAPGASAAT----------------AAVAGG------AGAAGA 584
            :|::||:              .:.|..|:.|                |....|      ||.|..
  Rat   380 ASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANH 444

  Fly   585 GG----------ATSATQ--VMSAANIYSSIGQPYAQEQSNFGAIYHHNAAAAAAAHYHHGHAHG 637
            |.          .||.|.  |:......:.:..|.:.:...|  :|.|......:.|.:|. .||
  Rat   445 GSPQLGEGMFQHQTSVTHQPVVRQCGPQTGLQSPGSLQPPEF--LYTHGVPRTLSPHQYHS-VHG 506

  Fly   638  637
              Rat   507  506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	111/201 (55%)
Tbx5	NP_001009964.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46		4/9 (44%)
		TBOX	53..241	CDD:238106	110/198 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..313		15/65 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..369		6/37 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910