Protein Alignment org-1 and Tbx4

DIOPT Version :10

• Sequence 1: NP_511085.2
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: XP_006247098.1
• Gene: Tbx4 / 303399
• RGDID: 1309057
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 178/591 - (30%)
• Similarity: 253/591 - (42%)
• Gaps: 152/591 - (25%)

  Fly   106 PDQSSSSSSSSVSLPTDYAGVHSEASMA-PTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSA 169
            |....:|:|::.::|        |.::| |...|||:::....|...:.|:            :|
  Rat    19 PALGETSNSNNTNVP--------EPALATPGLSGTALSSPPGQGADVAAAA------------AA 63

  Fly   170 ENGTVKPNSHNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIG 234
            .....:....||..|               |..|.||.:||..||||||||.||||||:::|::.
  Rat    64 AAAAAEQTIENIKVG---------------LHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVT 113

  Fly   235 GLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSF 299
            |::|...||.::|.||.||  :||.|.::.|:|||||:|..|.|::|||||||.|::||:|:|||
  Rat   114 GMNPKTKYILLIDIVPADD--HRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSF 176

  Fly   300 DKLKLTNNQLDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAY 364
            .|||||||.||..|||||||||:||||.|:|.....||...:|   :.|.|.:||||||.:||:|
  Rat   177 QKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKN---TAFCTHVFPETSFISVTSY 238

  Fly   365 QNQRVTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQ 429
            ||.::|||||.:||||||||  |::|               |..|:.:.|.:
  Rat   239 QNHKITQLKIENNPFAKGFR--GSDD---------------SDLRVARLQSK------------- 273

  Fly   430 QQQQLKERTAATSNFGLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQ 494
                                |..:..:...:|:....||.|.|..|..
  Rat   274 --------------------EYPVISKSIMRQRLVSSQLSAKPDVSPL----------------- 301

  Fly   495 QQHQQQQQQQHQSQQQHLHQQHQANQQQSL-LQQSQNHTQYGSYHHAYQAQV-----------QS 547
              |...|..||...:...|.|..|.:.|.| |...........::|..:.:.           :|
  Rat   302 --HSTHQALQHYQYENGAHMQFAAAEPQDLPLNTFPTQRDSSLFYHCLKRRADSARHLDLPCKRS 364

  Fly   548 HPLTPHSSSS----ASPP----ATAAPG-ASAATAAVA-----GGAGAAGAGGATSATQVMSAAN 598
            :..||.|...    .|||    ...:|. .|..|...|     .|...||............:.|
  Rat   365 YLETPSSVGDDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSSSGPEIAGVSAVDDLPPPPLSCN 429

  Fly   599 IYSSIGQ------------PYAQEQSNFGA-IYHHNAAAAAAAHYHHGHAHGHAH---SHAHAHA 647
            :::|:..            ||....::|.| ........||.:....|:||...:   |.:....
  Rat   430 MWTSVSPYTSYSVQTMETVPYQPFPTHFTATTMMPRLPIAAQSAQPPGNAHFSVYNQLSQSQVRE 494

  Fly   648 HGPYAS 653
            .||.||
  Rat   495 RGPSAS 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_511085.2	T-box_TBX1_10-like	195..385	CDD:410313	108/189 (57%)
Tbx4	XP_006247098.1	T-box_TBX4_5-like	75..259	CDD:410315	111/205 (54%)