Protein Alignment org-1 and Tbx4

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_035666.2
• Gene: Tbx4 / 21387
• MGIID: 102556
• Length: 552
• Species: Mus musculus
• Alignment Length: 591
• Identity: 172/591 - (29%)
• Similarity: 249/591 - (42%)
• Gaps: 155/591 - (26%)

  Fly   106 PDQSSSSSSSSVSLPTDYAGVHSEASMA-PTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSA 169
            |....:|::|:.:.|        |.::| |...|.|:::....|...:.|:.           :|
Mouse    19 PALGEASNTSTTNAP--------EPALATPGLSGAALSSPPGQGADVAAAAA-----------AA 64

  Fly   170 ENGTVKPNSHNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIG 234
            ...|::    ||..|               |..|.||.:||..||||||||.||||||:::|::.
Mouse    65 AEQTIE----NIKVG---------------LHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVT 110

  Fly   235 GLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSF 299
            |::|...||.::|.||.||  :||.|.::.|:|||||:|..|.|::|||||||.|::||:|:|||
Mouse   111 GMNPKTKYILLIDIVPADD--HRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSF 173

  Fly   300 DKLKLTNNQLDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAY 364
            .|||||||.||..|||||||||:||||.|:|.....||...:|   :.|.|.:||||||.:||:|
Mouse   174 QKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNAFGSKN---TAFCTHVFPETSFISVTSY 235

  Fly   365 QNQRVTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQ 429
            ||.::|||||.:||||||||  |::|               |..|:.:.|.:
Mouse   236 QNHKITQLKIENNPFAKGFR--GSDD---------------SDLRVARLQSK------------- 270

  Fly   430 QQQQLKERTAATSNFGLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQ 494
                                |..:..:...:|:....||.|.|..|..
Mouse   271 --------------------EYPVISKSIMRQRLVSSQLSAKPDVSPL----------------- 298

  Fly   495 QQHQQQQQQQHQSQQQHLHQQHQANQQQSL-LQQSQNHTQYGSYHHAYQAQVQSHPL-------- 550
              |...|..||...:...|.|..|.:.|.| |...........::|..:.:..:..|
Mouse   299 --HSAHQALQHYQYENGAHMQFAAAEPQDLPLNTFPTQRDSSLFYHCLKRRDSARHLDLPCKRSY 361

  Fly   551 ----------------TPHSSSSASPPATAAPGASAATAAVAGGAGAAGAGGATSATQVMSAANI 599
                            .|:.....||...:......|....:.|...||............:.|:
Mouse   362 LETPSSVGDDHYFRSPPPYDQQMLSPSYCSEVTPREACMYSSSGPEIAGVSAVDDLPPPPLSCNM 426

  Fly   600 YSSIGQ------------PYAQEQSNFGA--IYHHNAAAAAAAHYHHGHAHGHAH---SHAHAHA 647
            ::|:..            ||....::|.|  :.......||.:....|:||...:   |.:....
Mouse   427 WTSVSPYTSYSVQTMETVPYQPFPAHFTATTVMPRLPTIAAQSAQPPGNAHFSVYNQLSQSQVRE 491

  Fly   648 HGPYAS 653
            .||.||
Mouse   492 RGPSAS 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	110/193 (57%)
Tbx4	NP_035666.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		9/38 (24%)
		TBOX	71..260	CDD:238106	114/225 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910