Protein Alignment org-1 and Tbx15

DIOPT Version :9

• Sequence 1: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_033349.2
• Gene: Tbx15 / 21384
• MGIID: 1277234
• Length: 602
• Species: Mus musculus
• Alignment Length: 618
• Identity: 191/618 - (30%)
• Similarity: 260/618 - (42%)
• Gaps: 173/618 - (27%)

  Fly    53 IEACIQTAGKDRSSYKPLEQIDAKLADIETHSTGSTGTANSNSSTSSISNPSCPDQSSSSSSSSV 117
            :||.|.:..|     :.|...:.|..|:...:....|........::......||...|:.|.|.
Mouse    20 VEALIGSNKK-----RKLRDWEEKGLDLSMEALSPAGPLGDTDDPATHGLEPHPDSEQSTGSDSE 79

  Fly   118 SLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVKPNSHNIS 182
            .|        :|.:....:..|.:.:.:||.|.|:.:
Mouse    80 VL--------TERTSCSFSTHTDLASGAAGPVPAAMS---------------------------- 108

  Fly   183 KGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMD 247
                     |:.:..|.|:...||.:||..||||||||.||||||..:|:|.|||||..|...||
Mouse   109 ---------SMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMD 164

  Fly   248 FVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDEN 312
            .||:|:|||||.:|:|.|:|||.||...|||:::||||.|.|..||:|:|||||||||||:||:.
Mouse   165 IVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQ 229

  Fly   313 GHIILNSMHRYQPRFHLV-------YLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVT 370
            |||||:|||:||||.|::       ..|.|...:.:.     .:||.||||.||.|||||||::|
Mouse   230 GHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDG-----VKTFNFPETVFTTVTAYQNQQIT 289

  Fly   371 QLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQLK 435
            :|||..|||||||||.|.|  .||..:.|     |:.|..:.                      .
Mouse   290 RLKIDRNPFAKGFRDSGRN--RTGLEAIM-----ETYAFWRP----------------------P 325

  Fly   436 ERTAATSNFGLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQQHQQQ 500
            .||            |..|.....|:|||. ....:|::|||...||
Mouse   326 VRT------------LTFEDFTTMQKQQGG-STGTSPTTSSTGTPSP------------------ 359

  Fly   501 QQQQHQSQQQHLHQQ-------HQA-NQQQSLLQQSQ----NHTQYGSYHHAYQAQVQSHP---- 549
                  |...||...       |.| |......::||    |.:.|.....:..|.:||:|
Mouse   360 ------SASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSD 418

  Fly   550 -----LTPHSSSSASPPATAAPGASAATAAVAGG----------------AGAAGAGGATSATQV 593
                 |...::|:..|..|..|   ..|.::..|                .|..|:...:....|
Mouse   419 SGYNRLQSGTASATQPSETFMP---QRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQFQYV 480

  Fly   594 MSAANIYSSIGQPYA-----QEQSNFGAIYHHN 621
            |.|.|..||...|:.     .:||::.|...||
Mouse   481 MQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHN 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	115/200 (58%)
Tbx15	NP_033349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..95		9/59 (15%)
		TBOX	113..308	CDD:238106	115/199 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..369		13/55 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..444		4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940