DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1440 and nfrkb

DIOPT Version :9

Sequence 1:	NP_001285018.1	Gene:	CG1440 / 31776	FlyBaseID:	FBgn0030038	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_989207.1	Gene:	nfrkb / 394815	XenbaseID:	XB-GENE-6258496	Length:	1265	Species:	Xenopus tropicalis

Alignment Length:	396	Identity:	75/396 - (18%)
Similarity:	126/396 - (31%)	Gaps:	135/396 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 YWDKIERCNYFLNNVVKTAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITK----------HG 255
            :::.:.|..:  .||:..:||     ..|..||.:.|..:..|.:.::..:.:          |
Frog    49 FFEVVSRDTW--KNVLSDSQR-----EHLKQFLPVFPDDNANQQEKIIQSLFRGDNFRFGNPLH- 105

  Fly   256 LMPKKCFPES-FSCESSLRMNAILKSKLREY------------------ARNLRVLMEKNPTDEE 301
             :.:|.|.:. |:.|........|||:.:.|                  .:.|..|..||..|:.
Frog   106 -IAQKLFRDGHFNPEVVKYRQLCLKSQYKRYLTSQQQYFHKLLKQILASRKELLDLARKNGPDQV 169

  Fly   302 IACKIQEQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSIGPVSSLEFYERYVKPHFNVEDKVC 366
            :.           |........|.|..|                   ....||:|....|:|: |
Frog   170 LK-----------KKPSSLRNTPEERET-------------------RAQCRYLKILREVKDE-C 203

  Fly   367 ----LVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVV----TKSLKAGEAVWFGC 423
                |.::....||:.......|              .||.:.|.|:    |:.:|.
Frog   204 GDGTLSSEEEDLSSWLPESPTHC--------------PSVAVPLRVIPTLSTQDMKT-------- 246

  Fly   424 EVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADR--LIYGESAMTHAMVFTAVSVDKSG--- 483
                  |.||...:   ||.||:.....:....::|.  ||....:|...|  |.|:..:.|
Frog   247 ------ADKQEFTN---HDLKLLLRRHREKRKRQSDHPDLITDNLSMNDIM--TRVNAGRKGSLA 300

  Fly   484 -----VAQKLRVENSWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDMDPIVLPAW 543
                 ...|.||:..  :|:.:|....:..:         |.|...:|::.    |:.|.|||..
Frog   301 ALFDLATMKKRVKEK--DDKKKKKLKTIKTE---------VEDYPDMPDEA----DIMPAVLPPE 350

  Fly   544 DPMGTL 549
            .|..||
Frog   351 TPQVTL 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1440	NP_001285018.1	Peptidase_C1_2	102..547	CDD:281100	73/392 (19%)
nfrkb	NP_989207.1	NFRKB_winged	380..477	CDD:291154
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	670..693
		PHA03255	700..>840	CDD:165513
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	705..738
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1000..1033
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1234..1265
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165177306
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930