DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1440 and blmh

DIOPT Version :9

Sequence 1:	NP_001285018.1	Gene:	CG1440 / 31776	FlyBaseID:	FBgn0030038	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_956312.1	Gene:	blmh / 336541	ZFINID:	ZDB-GENE-030131-8485	Length:	453	Species:	Danio rerio

Alignment Length:	440	Identity:	251/440 - (57%)
Similarity:	327/440 - (74%)	Gaps:	3/440 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 KNFYSEPKNLLAQNVCSRVDPFDVCLSRKALETTNHVFNYKVETEGKPVTNQRSSGRCWLFAALN 177
            |.|.|||:.||||||.:.:||.:|||.|:.::.|.|:|.:.:.|||||||||::|||||:|:.||
Zfish    15 KRFRSEPRYLLAQNVSTCIDPLEVCLHRQTVQDTVHIFQHSIPTEGKPVTNQKNSGRCWIFSCLN 79

  Fly   178 CIRLPFMKNYNLDEFEFSQAFLFYWDKIERCNYFLNNVVKTAQRGEKVDGRLVSFLLLDPTSDGG 242
            .:||||||.:|::||||||::||:|||:|||.:||:..|:||||.|.||||||.|||.:||:|||
Zfish    80 VMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFLHACVETAQRKEPVDGRLVQFLLSNPTNDGG 144

  Fly   243 QWDMLVNLITKHGLMPKKCFPESFSCESSLRMNAILKSKLREYARNLRVLMEKNPTDEEIACKIQ 307
            |||||||||.|:|::||||||||.|.|:|.|||.||..|:|||...||.::....|..||:..|.
Zfish   145 QWDMLVNLIEKYGVVPKKCFPESHSSEASRRMNDILNHKMREYCLRLRNMVASESTKTEISETID 209

  Fly   308 EQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSIGPVSSLEFYERYVKPHFNVEDKVCLVTDPR 372
            ..:.|:::|..:|||.|.:|..|||.||.||:..:||::.||||..:|||.:|::||:|||.|||
Zfish   210 TMIEEVFRVASVCLGSPPDTICWEYRDKDKNFHHLGPLTPLEFYTEHVKPLYNLQDKICLVNDPR 274

  Fly   373 PTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTKSLKAGEAVWFGCEVSKRFASKQGIED 437
            |.:.|.:.|||:.|.|:||||..|||||.||||......|:|.||||||||:|.|.|.||.||.|
Zfish   275 PQNPYGKLYTVEFLSNMVGGRKTLYNNQPVELLKKAAADSIKKGEAVWFGCDVGKHFHSKLGIND 339

  Fly   438 VDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAMVFTAVS--VDKSGVAQKLRVENSWGEDRGE 500
            ::|.:..|||.:.:: ..|||:|||||:|.|||||:.|||:  |.|....:|.|||||||:|||.
Zfish   340 MNVFNHDLVFGVSVK-NLSKAERLIYGDSMMTHAMILTAVTDKVGKEACYEKWRVENSWGDDRGN 403

  Fly   501 KGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDMDPIVLPAWDPMGTLA 550
            ||||:|..:||.|:.:||||||.::..:||.|...||:|||||||||.||
Zfish   404 KGYLIMTDEWFSEYVYEVVVDKSFLSPEVLDVMQKDPVVLPAWDPMGALA 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1440	NP_001285018.1	Peptidase_C1_2	102..547	CDD:281100	247/435 (57%)
blmh	NP_956312.1	Peptidase_C1B	5..450	CDD:238328	247/435 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595589
Domainoid	1	1.000	533	1.000	Domainoid score	I269
eggNOG	1	0.900	-	-		E1_COG3579
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H330
Inparanoid	1	1.050	537	1.000	Inparanoid score	I1160
OMA	1	1.010	-	-		QHG62787
OrthoDB	1	1.010	-	-		D308225at33208
OrthoFinder	1	1.000	-	-		FOG0007157
OrthoInspector	1	1.000	-	-		oto39808
orthoMCL	1	0.900	-	-		OOG6_105635
Panther	1	1.100	-	-	LDO	PTHR10363
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2049
SonicParanoid	1	1.000	-	-		X6034
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800