DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1440 and Blmh

DIOPT Version :9

Sequence 1:	NP_001285018.1	Gene:	CG1440 / 31776	FlyBaseID:	FBgn0030038	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_001029335.1	Gene:	Blmh / 287552	RGDID:	1304668	Length:	455	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	256/466 - (54%)
Similarity:	335/466 - (71%)	Gaps:	15/466 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 NSGKNSTHRFAETSVITNQLLEKWRKNFYSEPKNLLAQNVCSRVDPFDVCLSRKALETTNHVFNY 152
            |:|.||....|        |::|    ..|:|:.:|||||.:..|..|:||.|..::...|||.:
  Rat     3 NAGLNSEKVAA--------LIQK----LNSDPQFVLAQNVGTTHDLLDICLKRATVQGAQHVFQH 55

  Fly   153 KVETEGKPVTNQRSSGRCWLFAALNCIRLPFMKNYNLDEFEFSQAFLFYWDKIERCNYFLNNVVK 217
            .|..||||||||:||||||:|:.||.:||||||.:|::||||||::||:|||:|||.:|||..|.
  Rat    56 VVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFLNAFVD 120

  Fly   218 TAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKKCFPESFSCESSLRMNAILKSKL 282
            |||:.|..|||||.:||::||:||||||||||::.|:|::||||||||.:.|::.|||.||..|:
  Rat   121 TAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPESHTTEATRRMNDILNHKM 185

  Fly   283 REYARNLRVLMEKNPTDEEIACKIQEQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSIGPVSS 347
            ||:...||.|:....|..||:......|.||::||.||||.|.|||||||.||.|||..:||::.
  Rat   186 REFCIRLRNLVHSGATKGEISSTQDAMMEEIFRVVCICLGNPPETFTWEYRDKDKNYHKVGPITP 250

  Fly   348 LEFYERYVKPHFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTKS 412
            |:||:.:|||.||:|||:|.|.||||...|::.||||.|.|:||||..|||||.::.|..:|..|
  Rat   251 LQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKKMVAAS 315

  Fly   413 LKAGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAMVFTAV 477
            ::.||||||||:|.|.|..|.|:.|::|:|.:|||.:.:: ..:||:||.:|||.|||||.||||
  Rat   316 IRDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLK-NMNKAERLAFGESLMTHAMTFTAV 379

  Fly   478 SV--DKSGVAQKLRVENSWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDMDPIVL 540
            |.  |:.|...|.|||||||||.|.||||.|..:||.|:.:|||||||:|||:||.|.:.:||||
  Rat   380 SEKDDQEGAFVKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQEPIVL 444

  Fly   541 PAWDPMGTLAQ 551
            |||||||.||:
  Rat   445 PAWDPMGALAE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1440	NP_001285018.1	Peptidase_C1_2	102..547	CDD:281100	247/446 (55%)
Blmh	NP_001029335.1	Peptidase_C1_2	5..451	CDD:281100	251/458 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353453
Domainoid	1	1.000	528	1.000	Domainoid score	I280
eggNOG	1	0.900	-	-		E1_COG3579
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H330
Inparanoid	1	1.050	532	1.000	Inparanoid score	I1174
OMA	1	1.010	-	-		QHG62787
OrthoDB	1	1.010	-	-		D308225at33208
OrthoFinder	1	1.000	-	-		FOG0007157
OrthoInspector	1	1.000	-	-		oto95672
orthoMCL	1	0.900	-	-		OOG6_105635
Panther	1	1.100	-	-	LDO	PTHR10363
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6034
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770