DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1440 and Blmh

DIOPT Version :9

Sequence 1:	NP_001285018.1	Gene:	CG1440 / 31776	FlyBaseID:	FBgn0030038	Length:	551	Species:	Drosophila melanogaster
Sequence 2:	NP_848760.1	Gene:	Blmh / 104184	MGIID:	1345186	Length:	455	Species:	Mus musculus

Alignment Length:	471	Identity:	258/471 - (54%)
Similarity:	335/471 - (71%)	Gaps:	19/471 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 NNNSANSGKNSTHRFAETSVITNQLLEKWRKNFYSEPKNLLAQNVCSRVDPFDVCLSRKALETTN 147
            ||...||.|.|.            |::|    ..|:|:.:|||||.:..|..|:||.|..::...
Mouse     2 NNAGLNSEKVSA------------LIQK----LNSDPQFVLAQNVGTTHDLLDICLRRATVQGAQ 50

  Fly   148 HVFNYKVETEGKPVTNQRSSGRCWLFAALNCIRLPFMKNYNLDEFEFSQAFLFYWDKIERCNYFL 212
            |||.:.|..||||||||:||||||:|:.||.:||||||.:|::||||||::||:|||:|||.:||
Mouse    51 HVFQHVVPQEGKPVTNQKSSGRCWIFSCLNVMRLPFMKKFNIEEFEFSQSYLFFWDKVERCYFFL 115

  Fly   213 NNVVKTAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKKCFPESFSCESSLRMNAI 277
            |..|.|||:.|..|||||.:||::||:||||||||||::.|:|::||||||||.:.|::.|||.|
Mouse   116 NAFVDTAQKKEPEDGRLVQYLLMNPTNDGGQWDMLVNIVEKYGVVPKKCFPESHTTEATRRMNDI 180

  Fly   278 LKSKLREYARNLRVLMEKNPTDEEIACKIQEQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSI 342
            |..|:||:...||.|:....|..||:......|.||::||.||||.|.|||||||.||.|||..|
Mouse   181 LNHKMREFCIRLRNLVHSGATKGEISSTQDAMMEEIFRVVCICLGNPPETFTWEYRDKDKNYHKI 245

  Fly   343 GPVSSLEFYERYVKPHFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLA 407
            ||::.|:||:.:|||.||:|||:|.|.||||...|::.||||.|.|:||||..|||||.::.|..
Mouse   246 GPITPLQFYKEHVKPLFNMEDKICFVNDPRPQHKYNKLYTVDYLSNMVGGRKTLYNNQPIDFLKK 310

  Fly   408 VVTKSLKAGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAM 472
            :|..|:|.||||||||:|.|.|..|.|:.|::|:|.:|||.:.:: ..:||:||.:|||.|||||
Mouse   311 MVAASIKDGEAVWFGCDVGKHFNGKLGLSDMNVYDHELVFGVSLK-NMNKAERLAFGESLMTHAM 374

  Fly   473 VFTAVSV--DKSGVAQKLRVENSWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDM 535
            .|||||.  ::.|...|.|||||||||.|.||||.|..:||.|:.:|||||||:|||:||.|.:.
Mouse   375 TFTAVSEKDNQEGTFVKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDKKHVPEEVLAVLEQ 439

  Fly   536 DPIVLPAWDPMGTLAQ 551
            :|||||||||||.||:
Mouse   440 EPIVLPAWDPMGALAE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1440	NP_001285018.1	Peptidase_C1_2	102..547	CDD:281100	248/446 (56%)
Blmh	NP_848760.1	Peptidase_C1_2	5..451	CDD:281100	252/462 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849791
Domainoid	1	1.000	527	1.000	Domainoid score	I294
eggNOG	1	0.900	-	-		E1_COG3579
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H330
Inparanoid	1	1.050	531	1.000	Inparanoid score	I1197
Isobase	1	0.950	-	0	Normalized mean entropy	S1254
OMA	1	1.010	-	-		QHG62787
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007157
OrthoInspector	1	1.000	-	-		oto92103
orthoMCL	1	0.900	-	-		OOG6_105635
Panther	1	1.100	-	-	LDO	PTHR10363
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2049
SonicParanoid	1	1.000	-	-		X6034
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740