Protein Alignment Miga and Miga1

DIOPT Version :10

• Sequence 1: NP_572476.2
• Gene: Miga / 31775
• FlyBaseID: FBgn0030037
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_038959810.1
• Gene: Miga1 / 362058
• RGDID: 1559958
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 579
• Identity: 177/579 - (30%)
• Similarity: 287/579 - (49%)
• Gaps: 96/579 - (16%)

  Fly     5 MPASWSSGGSLLPFRVSTTTKVVLFSLTAGVALMSVLSRFLRRR-------KPPRP-------PR 55
            :|.||....|.:.| .....|:.:.:..:.|:::.:...|.|||       .|..|       .|
  Rat    23 LPVSWYYSLSQIKF-PPAAKKLFMVTAVSAVSVIFLAHHFKRRRGKQKGKVLPWEPEHLLLEHTR 86

  Fly    56 RARKYTGRRNRNSMRSPNDLISIAGSKASARSGSPVGSTLAYSDRLSMASGSIG--VGVLGVQNA 118
            ||....|....:|.::....:|....|.|.....|.|..|:   |.|.::.|:|  ..|....:.
  Rat    87 RAASDKGSSCSSSRQNLTLSLSSTKDKGSQSCNYPNGGLLS---RYSGSAQSLGSVQSVNSCHSC 148

  Fly   119 GPGSS--------------VVTQLTAQQLGMMGMEALDTVINFWEDAL-------------AAHY 156
            ..|:|              .:...|.:.|.:||||..:..::.||.||             :...
  Rat   149 ACGNSNSWDKADDDDVRLVNIPVTTPENLYLMGMELFEEALHRWEQALTFRSRQAEDEACSSVKL 213

  Fly   157 SPGGLPA-----LLTTAED-------SEFCREIQNLLEMAYTLQEQSELLF-----------LDQ 198
            ..|...|     :.|:||:       :||..:::.||:.||.|||:.|...           .|:
  Rat   214 GAGDAIAEESVDVRTSAEEQASDIISTEFIHKLEALLQRAYRLQEEFEAALGGSDPDSLANDTDK 278

  Fly   199 RSVLFREEHSIDEAEEEAGEADDDRRSRKSGSVLSRAGSDPNFDSAESFASALDQVADLREFDGF 263
            .:.|     |:.|..:|.|..|                 ..|.|||:.|||| .::|:.||....
  Rat   279 DTDL-----SVRETVDEFGLPD-----------------TANIDSADLFASA-TELAEHREAQQA 320

  Fly   264 IE-TSYEEYPLFQSALKHHDEYTVPCRTIRAELMHCSTDTEYLAKLHCVRLAFQFLFKDPAVGQW 327
            :. .|:...|.::.|:...:|..:..|.:|.|::.|..|:::||||||:|.|||.:..:.....:
  Rat   321 LSLESFCRCPFYEEAMHLVEEGKIHSRVLRTEMLECLGDSDFLAKLHCIRQAFQLILAEADNRSF 385

  Fly   328 ICDAGRQILTDLLCLGDKDTKEFLVGYEDMVNYLHDSNNWPCIQMELEQRNVKAMTFYDICLDFI 392
            :.::||:||:.|:....|:.|:|...:::|:.:|..:::|...:|||..|.||.:.|||:.||||
  Rat   386 LAESGRKILSALIVKARKNPKKFQDVFDEMIYFLEQTDHWDSTEMELAARGVKNLNFYDVVLDFI 450

  Fly   393 ILDSFKDLDAPPASVTAVVQNRWLSNGFKETALTTAVWSVLKAKKRMLK-FPNGFMSHFYVISEQ 456
            ::|||:||:.||.|:.:||.|.|||..|||||:.::.|||||.|::.:| ..:||.:|||.|.|.
  Rat   451 LMDSFEDLENPPTSIQSVVTNHWLSASFKETAVASSCWSVLKQKRQQMKQISDGFFAHFYAICEH 515

  Fly   457 ISPLMAWGFFGPNENLRDICHYFREELLAFLGDIFSFQKSRFTTIEEFSQDVLQHMQTR 515
            |||::||||.||..:|.|:|.:|:.::|.||.|||.|:|.|:::|:..::| |.|:..|
  Rat   516 ISPVLAWGFLGPRNSLYDLCCFFKNQVLFFLKDIFDFEKVRYSSIDTLAED-LTHLLIR 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Miga	NP_572476.2	Miga	13..523	CDD:463034	174/571 (30%)
Miga1	XP_038959810.1	Miga	27..582	CDD:463034	175/575 (30%)