Protein Alignment Miga and miga-1

DIOPT Version :10

• Sequence 1: NP_572476.2
• Gene: Miga / 31775
• FlyBaseID: FBgn0030037
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_506105.2
• Gene: miga-1 / 179700
• WormBaseID: WBGene00010465
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 153/538 - (28%)
• Similarity: 259/538 - (48%)
• Gaps: 106/538 - (19%)

  Fly    24 TKVVLFSLTAGVALMSVLSRFLR--RRK--------------------PPRPPRRARKYTGRRNR 66
            ||..:.|:.||:.:..|.:.|:|  |:|                    .|..|...|..:||
 Worm    20 TKRTVLSVAAGIGIGIVFANFVRYWRQKREAKVPQSIIEEIGKDADIIVPSAPSLRRSQSGR--- 81

  Fly    67 NSMRSPNDLISIAGSKASARSGSPVGSTLAYSDRLSMASGSIGVGVLGVQNAGPGSSVVTQL--T 129
             .||.|    |..|.::|.|      :::..:.:.||  ..|...:..      |..:.|:|  |
 Worm    82 -GMRPP----SSQGERSSLR------NSIRQNSQRSM--NPIEADITS------GQELCTELRKT 127

  Fly   130 AQQLGMMGMEALDTVINFWEDALAAHYSPGGLPALLTTAEDSEFCREIQNLLEMAYTLQEQSELL 194
            .:::    ...|:.|.|                   .:::|.|...:|:.:|:  ...|.:.|::
 Worm   128 IEKV----HHNLEMVKN-------------------RSSKDMERSIKIEGILK--GLKQVEDEIV 167

  Fly   195 FLDQRSVLFREE----HSIDEAEEEAGEADDDRRSRKSGSVLSRAGSDPNFDSA-ESFASALDQ- 253
            .|..:...||::    :|:......||.....|  .::.|||    ||.:|.|| |.||..:|.
 Worm   168 LLVPQMEDFRDDNMEFYSVSGGSGYAGSVRTGR--SRTLSVL----SDDSFRSAVEEFACDIDDI 226

  Fly   254 --VADLREFD----GFIETSYEEYPLFQSALKHHDEYTVPCRTIRAELMHCSTDTEYLAKLHCVR 312
              |:|....|    .|::..      .|:||....:|    |..|.|...|.::|::.|||:|||
 Worm   227 DFVSDAANLDKNELRFLDEG------MQAALNGEVKY----RKSRMEFCKCDSETDFAAKLYCVR 281

  Fly   313 LAFQFLFKDPAVGQWICDAGRQILTDLLCLGDKDTKEFLVGYEDMVNYLHDSNNWPCIQMELEQR 377
            .|.....||.....|:...||.:|.|.:....:|..:|...|::|:.|:.:..|...::.::|.|
 Worm   282 QALTNALKDEHKRVWLAKCGRTLLADFIRHTKQDPVKFFNAYDEMLEYVSNDRNEEQLRQDVEGR 346

  Fly   378 NVKAMTFYDICLDFIILDSFKDLDAPPASVTAVVQNRWLSNGFKETALTTAVWSVLKAKKRMLKF 442
            .|....|||:.:||||||:|:||.:||::|.:|.:|.::|...|.:.|.|.:||::|:|::.||.
 Worm   347 GVCETGFYDVAIDFIILDAFEDLKSPPSAVYSVTKNYFMSMSMKYSTLNTIIWSIIKSKRQRLKN 411

  Fly   443 PNGFMSHFYVISEQISPLMAWGFFGPNENLRDICHYFREELLAFLGDIFSFQKSRFTTIEEFSQD 507
            |:||::.||.|||.:.|.:..||.|.:|.|.::|.||:|:::.|:.|:|:.||..:.::||.|:|
 Worm   412 PDGFIAKFYNISETVMPAITLGFLGTDERLGELCQYFKEQVVQFVLDVFNTQKVCYRSLEEMSED 476

  Fly   508 V-------LQHMQTRVNN 518
            |       |:.:|||::|
 Worm   477 VWIVMRNRLEAVQTRMSN 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Miga	NP_572476.2	Miga	13..523	CDD:463034	153/538 (28%)
miga-1	NP_506105.2	Miga	6..492	CDD:463034	151/534 (28%)