DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIG-T and gpi16

DIOPT Version :9

Sequence 1:	NP_572475.1	Gene:	PIG-T / 31772	FlyBaseID:	FBgn0030035	Length:	633	Species:	Drosophila melanogaster
Sequence 2:	NP_596625.1	Gene:	gpi16 / 2539759	PomBaseID:	SPBC1604.15	Length:	545	Species:	Schizosaccharomyces pombe

Alignment Length:	581	Identity:	166/581 - (28%)
Similarity:	267/581 - (45%)	Gaps:	85/581 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DERFHEELVVRPLSGDHVNTYFQFTTRWHYGEKDNLYHT--------QLTPRVIAELLQQFAVKE 80
            ||.:.|.|.::..|..:....|.|    ..|...:..|:        .|.|..||.::.:..|.|
pombe    25 DETYDESLFIKSFSSRYSYVSFAF----EIGASTDSTHSSVFSESSFSLFPLSIARVMDECQVSE 85

  Fly    81 LHIGLTQGLWRYETW------GYPIVEATSGAEMWAWFSGANLTNRDVDRQWKELANVFSGVLCA 139
            |||..|:|.|.||.|      |:  .....|.|:||:     :.|....:.|.:|.|..||:|||
pombe    86 LHIRATRGRWDYENWKESPDNGF--YSGGLGFEVWAF-----MANDPSMKYWLKLTNQLSGLLCA 143

  Fly   140 SLNFVDNTNSIAPRHLIRPQFMPANGQRFVRYATLPREIVCTENLTPWKKLLPCGSASGFASLLN 204
            |||::|::|:..|:......|..:|..::  :|:||:|.||||||:|..|||||...:|.||||:
pombe   144 SLNYIDSSNTYQPQLSYPGSFSFSNNTQY--FASLPQEDVCTENLSPLFKLLPCKRKAGIASLLD 206

  Fly   205 SGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTANLVYDLRLFELSNNDFSLRRLFGMGLNGY 269
            |....:|.:||..:.|      :..:|..:...:...::.  .:.::..|.....:......:.|
pombe   207 SHLFFDTDWHSFSIDV------YPSENQSLASVKMGIIIQ--AVVDVERNGRRKGKTTFQPPSEY 263

  Fly   270 CELAESSKIYVQRNELGERYQLVPEPVHEVKTTRGGHSVVYSVYDMHEQFKEAGERLFNVAWLAP 334
            |...:...::...:.....:..|.:..|:|...|...|..:|     :.|...|:::...
pombe   264 CHDEDMDSLHCLMSGYSTEHHTVDDLFHKVPKERCLLSSTFS-----DVFVSNGDKIDTF----- 318

  Fly   335 KSANRRRNLAKP-----SLPPVTVHRYLLGHGQERGRIVTEVTNSHYDALPIMLQEVIPWYVHAY 394
             |.:...|:..|     ....|||.|.|...|...|.:.:.:.|.......|:..|..||:|..|
pombe   319 -SLDEAANIQIPIQSTSDNHTVTVDRSLSNDGNHWGSLSSTIYNPSSSPRTIVYFEKFPWFVRVY 382

  Fly   395 LHTLSIRRKPQRVNEYGGQRLTFKLLHYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKW 459
            ||||:|.....|:|    .:...:.|:|.|.:.|:..:.:||.|.:|..|:.::..:|:...|:.
pombe   383 LHTLTITLNGTRIN----TKDFIEKLYYQPLRDRKAGTMMEIQFSIPPHTNLIVHFNVEKTPLRL 443

  Fly   460 LEYPPDANHGHYIGSAIVSSQLPMGRNYTALPPEGHLFEHSFNATRPSYVLSLHTEALIVSLPTP 524
            .|||||||.|:.:..||:|                 :|:.  |.|:   :.||.|.||::.:|||
pombe   444 DEYPPDANRGYNLPPAIIS-----------------VFDE--NNTK---LCSLRTAALLMFIPTP 486

  Fly   525 DFSMPYNVICLACTVVALAFGPIHSVATKMII------VGRQTSAPKNFVKKIFNQLFRRG 579
            |||||||||....||:||.||.|.::.|:..:      ..||.|..:...:|||::  :||
pombe   487 DFSMPYNVIIFTSTVIALTFGGIFNLLTRRFVPQQSKFQNRQPSMLQRLKEKIFHK--KRG 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-T	NP_572475.1	Gpi16	27..553	CDD:282031	155/544 (28%)
gpi16	NP_596625.1	Gpi16	9..535	CDD:282031	161/567 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	203	1.000	Domainoid score	I640
eggNOG	1	0.900	-	-		E1_KOG2407
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	205	1.000	Inparanoid score	I973
OMA	1	1.010	-	-		QHG55326
OrthoFinder	1	1.000	-	-		FOG0003522
OrthoInspector	1	1.000	-	-		oto100797
orthoMCL	1	0.900	-	-		OOG6_103068
Panther	1	1.100	-	-	LDO	PTHR12959
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R513
SonicParanoid	1	1.000	-	-		X2402
TreeFam	1	0.960	-	-
	13	12.860