Protein Alignment nAChRalpha3 and LOC798522

DIOPT Version :9

• Sequence 1: NP_001285015.1
• Gene: nAChRalpha3 / 31767
• FlyBaseID: FBgn0015519
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: XP_001338964.6
• Gene: LOC798522 / 798522
• -ID: -
• Length: 488
• Species: Danio rerio
• Alignment Length: 766
• Identity: 200/766 - (26%)
• Similarity: 304/766 - (39%)
• Gaps: 289/766 - (37%)

  Fly     2 KWFQVTIDMILVLSFISSSTANPDAKRLYDDLLSNYNKLVRPVVNVTDALTVRIKLKLSQLIDVN 66
            :|.:|.:...|:|:..|.......|.:|.:||:.:|:..:|||.:...:|.|.:::.|||:.|::
Zfish     6 RWMEVMLLSALLLAEASHCAQGRFAHKLLNDLMEDYSSALRPVDDTDKSLNVTLQVTLSQIKDMD 70

  Fly    67 LKNQIMTTNLWVEQSWYDYKLKWEPKEYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKAT 131
            .:||::...||:.|.|:|..|||..::|.|:|::.:||..|||||:||||.||.:|...:.|...
Zfish    71 ERNQVLIAYLWIRQVWHDAHLKWSKEDYDGLEVIRIPSSLIWRPDLVLYNKADDDFSGPVDTNVV 135

  Fly   132 LNYTGRVEWRPPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDLRHIDELNGTNVVEVGV 196
            |.|||.:.|..|||.||||.:||.|||||.|.|.:.||||||:|.|||:.         :..|..
Zfish   136 LRYTGEITWDAPAITKSSCVVDVSYFPFDSQQCNLTFGSWTYNGNQVDIA---------MGSVSG 191

  Fly   197 DLSEFYTSVEWDILEVPAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTIL 261
            |||:|..:|||:...:||.:|...|.||.:||.|||:.:.::|::.||.:||::||..||||..|
Zfish   192 DLSDFVENVEWECHGMPATKNVIMYGCCSDPYPDITYTVLLQRRSSFYIINLLLPCFLISFLAPL 256

  Fly   262 VFYLPSDSGEKVSLSISILLSLTVFFLLLAEIIPPTSLVVPLLGKFVLFTMILDTFSICVTVLVL 326
            .||||:||||||||.:::||:||||.:::||.:|| |..|||:.|:.:.||.:.|.|..:|:.::
Zfish   257 SFYLPADSGEKVSLGVTVLLALTVFQMMVAESMPP-SESVPLIAKYYIATMTMITASTALTIFIM 320

  Fly   327 NIHFRSPQTHTMAPWVRTVFINQLPRFLVMRRPLYPISEMIKSSRRLMVRTCNGLELRDQIPPLP 391
            ||||...:...:..|.:.:.|:
Zfish   321 NIHFCGAEAKPVPYWAKVLIID------------------------------------------- 342

  Fly   392 PPVALSRMHHSPKTTSRSTSPHLQHRVQTYNLMDECGMGMGGGASTITGHLSSLYPPTMSTANQQ 456
                                                             ::|.::
Zfish   343 -------------------------------------------------YMSKIF---------- 348

  Fly   457 TSTTSSLIDAQYHNQYQQTGGSLLDHPLTPTKFRQMTSTSSQTGQNGSGNGNGNGGYGGHGQSGG 521
                                                                             
Zfish   349 ----------------------------------------------------------------- 348

  Fly   522 HHLYRQQSSCSANFSPLPQHAHQAHASTTTSDLGMANPNVIKSTTTVNSVATASTLADSCCSGTI 586
             .:|....||::.|.       ||..|
Zfish   349 -FVYEVGESCASPFG-------QAEES-------------------------------------- 367

  Fly   587 QIHQGMGAGAACQSSELLHHQQLHHQQMHHQQQQQQQQQHHHHQRPTTSAAAAAAAAAAGGPSTS 651
                                 :..|.|.||::.:.      ||.:...|
Zfish   368 ---------------------ESFHSQNHHRKHKL------HHPKGKIS---------------- 389

  Fly   652 AAAAAAAAAAAAGTPPPPPPPAGVCDILPACQREGGPHCCSGRGNVRQRWHTCPELHKAMDGVTY 716
                        |:|||..|.......:..|  |...:|....||:     .|..  |.:..|.|
Zfish   390 ------------GSPPPCCPEDHKSPFVLGC--ESCVYCGFRSGNL-----ACDT--KLLRNVEY 433

  Fly   717 IADQTRKEEESTRVK-EDWKYVAMVLDRLFLWIFTIAVVVGTAGIILQAPT 766
            ||:..| |:::|.:| .:||.||.|:||.|:|||.|.|.:.:..||.:|||
Zfish   434 IANCFR-EQKTTALKVAEWKKVAKVMDRFFMWIFFIMVFLMSILIIGKAPT 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha3	NP_001285015.1	Neur_chan_LBD	26..241	CDD:280998	93/214 (43%)
		Neur_chan_memb	248..>359	CDD:280999	46/110 (42%)
		Neur_chan_memb	<683..760	CDD:280999	27/77 (35%)
LOC798522	XP_001338964.6	Neur_chan_LBD	32..477	CDD:332142	189/732 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910