Protein Alignment nAChRalpha3 and GluClalpha

DIOPT Version :9

• Sequence 1: NP_001285015.1
• Gene: nAChRalpha3 / 31767
• FlyBaseID: FBgn0015519
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Alignment Length: 344
• Identity: 76/344 - (22%)
• Similarity: 151/344 - (43%)
• Gaps: 78/344 - (22%)

  Fly    15 SFISSSTAN-------PDAKRLYDDLL--SNYNKLVRPV-VNVTDA-LTVRIKL---KLSQLIDV 65
            |..|:|.||       ...|::.|.:|  ..|:..:||. :|.||. ..||:.:   .:|::.||
  Fly    15 SLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDV 79

  Fly    66 NLKNQIMTTNLWVEQSWYDYKLKWEPKEYGGVEMLHV-PSDHIWRPDIVLYNNADGNFE------ 123
            .::..:..|   ..:.|.|.:||::..: |.::.|.: .::.:|.||:...|..:|:|.
  Fly    80 TMEYSVQLT---FREQWTDERLKFDDIQ-GRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPN 140

  Fly   124 --VTLATKATLNYTGRVEWRPPAIYKSSCEIDVEYFPFDEQTCVMKFGS--WTYDGFQVDLRHI- 183
              :.:....::.|:.|:.      ...:|.::::.:|.|.|.|.::..|  ||.:    ||..:
  Fly   141 VYIRIFPNGSVLYSIRIS------LTLACPMNLKLYPLDRQICSLRMASYGWTTN----DLVFLW 195

  Fly   184 DELNGTNVVEVGVDLSEFYTSVEWDILEVPAVRNEKFYT-CCDE-----PYLDITFNITMRRKTL 242
            .|.:...||:               .|.:|....|||.| .|:.     .|..:..::..:|:..
  Fly   196 KEGDPVQVVK---------------NLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFS 245

  Fly   243 FYTVNLIIPCMGISFLTILVFYLPSDSG---EKVSLSISILLSLTVFFLLLAEIIPPTSLVVPLL 304
            :|.:.:.|||..:..::.:.|:|  |.|   .:|||.::.||::......:...:||.|
  Fly   246 YYLIQIYIPCCMLVIVSWVSFWL--DQGAVPARVSLGVTTLLTMATQTSGINASLPPVS------ 302

  Fly   305 GKFVLFTMILDTFS-ICVT 322
                 :|..:|.:: :|:|
  Fly   303 -----YTKAIDVWTGVCLT 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha3	NP_001285015.1	Neur_chan_LBD	26..241	CDD:280998	51/239 (21%)
		Neur_chan_memb	248..>359	CDD:280999	19/79 (24%)
		Neur_chan_memb	<683..760	CDD:280999
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	76/344 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030