Protein Alignment nAChRalpha3 and CG8916

DIOPT Version :9

• Sequence 1: NP_001285015.1
• Gene: nAChRalpha3 / 31767
• FlyBaseID: FBgn0015519
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 371
• Identity: 79/371 - (21%)
• Similarity: 154/371 - (41%)
• Gaps: 60/371 - (16%)

  Fly    14 LSFISSSTANPDAKR--------------LYDDLLSNYNKLVRPVVNVTDALTVRIKLKLSQLID 64
            ||:.||..:|....|              :.::||..|.:...|.........|:..:.:..:..
  Fly    82 LSYSSSEISNQRRVRRKAAADMLSRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGP 146

  Fly    65 VNLKNQIMTTNLWVEQSWYDYKLKWEPKEYGGVEMLHVP---SDHIWRPDIVLYNNADGNFE-VT 125
            |:..:...:.:.:..|.|.|.:|.::    |.::.|.:.   .|.|||||...||....... :|
  Fly   147 VSELDMDYSMDCYFRQYWRDKRLSFK----GPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMIT 207

  Fly   126 LATK-ATLNYTGRVEWRPPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDLRHIDELNGT 189
            :..| ..|:..|.:.:......|::|.::::.||.|.|:|.:..||:.|...|:.....::.:..
  Fly   208 VPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAV 272

  Fly   190 NVVEVGVDLSEFYTSVEWDILEV-----PAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNLI 249
            :.|. |:.|::|      |::.:     ..||.|.     |...|.:.||  ::|.|.::.:.:.
  Fly   273 SFVP-GMTLNQF------DLISMMHRNFTTVRREG-----DFSVLHVAFN--LKRHTGYFLIQVY 323

  Fly   250 IPCMGISFLTILVFYLPSD-SGEKVSLSISILLSLTVFFLLLAEIIPPTSLVVPLLGKFVLFTMI 313
            :||:.|..|:.:.|::..: :.::|||.::.:|:|:...|.....:|......      .|...:
  Fly   324 VPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYAT------ALDWFL 382

  Fly   314 LDTFSICVTVLV--LNIHF-------RSPQTHTMAPWVRTVFINQL 350
            |.:|..|:..|:  ..:|:       .|||....  |......|.|
  Fly   383 LMSFLYCIATLLEFAGVHYFTKLGSGESPQLEDQ--WEDICIANSL 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha3	NP_001285015.1	Neur_chan_LBD	26..241	CDD:280998	49/238 (21%)
		Neur_chan_memb	248..>359	CDD:280999	24/113 (21%)
		Neur_chan_memb	<683..760	CDD:280999
CG8916	NP_573090.3	LIC	92..598	CDD:273305	74/361 (20%)
		Neur_chan_LBD	111..315	CDD:280998	48/221 (22%)
		Neur_chan_memb	322..>403	CDD:280999	18/86 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100