Protein Alignment nAChRalpha3 and chrne

DIOPT Version :9

• Sequence 1: NP_001285015.1
• Gene: nAChRalpha3 / 31767
• FlyBaseID: FBgn0015519
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: XP_002941867.4
• Gene: chrne / 100497712
• XenbaseID: XB-GENE-979686
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 386
• Identity: 154/386 - (39%)
• Similarity: 238/386 - (61%)
• Gaps: 9/386 - (2%)

  Fly    13 VLSFISSSTAN-PDAKRLYDDLLSNYNKLVRPVVNVTDALTVRIKLKLSQLIDVNLKNQIMTTNL 76
            :|..:.:|.|| .:..||...|.:||:...||...:.|.:.|.:||.|:.|||:|.|.:.:|||:
 Frog    10 LLILLHNSLANESEESRLIKYLFTNYDSKARPSKGIDDVVPVSLKLTLTNLIDLNEKEETLTTNV 74

  Fly    77 WVEQSWYDYKLKWEPKEYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLATKATLNYTGRVEWR 141
            ||:.:|.|.:|.|...||||:.::.||.|.:|.|:|||.||.||||||.......::.||.:.|.
 Frog    75 WVQIAWQDDRLTWNETEYGGMPLVQVPHDMMWLPEIVLENNIDGNFEVAYYANVLVHSTGYIYWL 139

  Fly   142 PPAIYKSSCEIDVEYFPFDEQTCVMKFGSWTYDGFQVDLRHI-DELNGTNVVEVGVDLSEFYTSV 205
            ||||::|:|.|::.|||||.|.|.:.|.|.||....:||..: |:..|....:|.:|...|..:.
 Frog   140 PPAIFRSTCSIEITYFPFDWQNCSLVFRSKTYSANDIDLHLVADDETGLPFDQVDIDREAFTENG 204

  Fly   206 EWDILEVPA--VRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTILVFYLPSD 268
            ||.|:..||  :.|.| |:..|..|.:|.|.:.::||.|||.:|:|:||:.||.|.:||::||:.
 Frog   205 EWAIMHRPARKIVNPK-YSKEDLRYQEIVFILIIQRKPLFYIINIIVPCVLISSLVVLVYFLPAK 268

  Fly   269 S-GEKVSLSISILLSLTVFFLLLAEIIPPTSLVVPLLGKFVLFTMILDTFSICVTVLVLNIHFRS 332
            : |:|.::|||:||:.|||..|:|::||.|||.|||:||:::|.|.:.|..:...|:|||:..||
 Frog   269 AGGQKCTVSISVLLAQTVFLFLIAQMIPETSLSVPLIGKYLMFVMFVSTLIVLSCVIVLNVSLRS 333

  Fly   333 PQTHTMAPWVRTVFINQLPRFLVMRRPLYPISEMIKSSRRLMVRTCNGLELRDQIPPLPPP 393
            |.|||::..|:.:.:..||:|:.:|  :.|..|..::.|... |:..|:.|:.:...|..|
 Frog   334 PSTHTLSSKVKHMLLEVLPQFIHLR--VEPCDEGEETPRERR-RSSLGIMLKAEEYVLKKP 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha3	NP_001285015.1	Neur_chan_LBD	26..241	CDD:280998	87/217 (40%)
		Neur_chan_memb	248..>359	CDD:280999	50/111 (45%)
		Neur_chan_memb	<683..760	CDD:280999
chrne	XP_002941867.4	LGIC_ECD_nAChR_G	47..241	CDD:349830	80/194 (41%)
		Neur_chan_memb	248..491	CDD:397193	58/147 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910