DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1632 and TMPRSS11D

DIOPT Version :9

Sequence 1:NP_001245577.1 Gene:CG1632 / 31763 FlyBaseID:FBgn0030027 Length:1056 Species:Drosophila melanogaster
Sequence 2:NP_004253.1 Gene:TMPRSS11D / 9407 HGNCID:24059 Length:418 Species:Homo sapiens


Alignment Length:374 Identity:77/374 - (20%)
Similarity:115/374 - (30%) Gaps:143/374 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   689 CGVQSALFNAKQHLSLPKMSA-PGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQ--GQPRA 750
            ||....|....:...|....| .|.|||.|:|...:.|.|.|:||...|:||...||:  ..|| 
Human   173 CGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPR- 236

  Fly   751 TWMAIVGAVRLSAKAPWTQRRRIIGMI-----KSPVEGSTAALVRLETPVSYSDHVRPICLPDAL 810
            .|:|..|   :|...| ..|.|:..::     ||....:..||||||..|:::..:..:|||.|.
Human   237 DWIATSG---ISTTFP-KLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAAT 297

  Fly   811 QRRLLQQPPAQRRSHVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQ 875
            |    ..||                                                        
Human   298 Q----NIPP-------------------------------------------------------- 302

  Fly   876 EDHFGGESAASYMPKAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIATKAPILAAVPA 940
                   .:.:|:....|  ||..|:.:|:                                :..
Human   303 -------GSTAYVTGWGA--QEYAGHTVPE--------------------------------LRQ 326

  Fly   941 AQEQIWTN--CNTLGWSRQRDHLQRVQLKMGDMAPCENVSIATVNSMCMEATYQKYDCTQEEYSG 1003
            .|.:|.:|  ||                     ||...........:|........|..|.:..|
Human   327 GQVRIISNDVCN---------------------APHSYNGAILSGMLCAGVPQGGVDACQGDSGG 370

  Fly  1004 APVQCLIPGTNQWALIGVSSWRIACG-PTGVERPRMYDKIASNAAWIRE 1051
            ..||  ......|.::|:.||...|| |   ::|.:|.::.:...|||:
Human   371 PLVQ--EDSRRLWFIVGIVSWGDQCGLP---DKPGVYTRVTAYLDWIRQ 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1632NP_001245577.1 SEA 232..327 CDD:279699
CRD_FZ 384..502 CDD:143549
PRKCSH-like <503..>582 CDD:193472
LDLa 536..571 CDD:238060
Tryp_SPc 708..>809 CDD:304450 38/108 (35%)
TMPRSS11DNP_004253.1 SEA 48..143 CDD:279699
Tryp_SPc 186..412 CDD:214473 71/357 (20%)
Tryp_SPc 187..415 CDD:238113 74/360 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165143824
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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