DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and Sfrp1

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001263641.2	Gene:	Sfrp1 / 84402	RGDID:	621074	Length:	314	Species:	Rattus norvegicus

Alignment Length:	164	Identity:	42/164 - (25%)
Similarity:	61/164 - (37%)	Gaps:	42/164 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   382 PRRC--SPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQP 444
            |.:|  .|::|..|..|||.....||||.|.:..::.:....:..|::..||.....|:|.|..|
  Rat    55 PPQCVDIPVDLRLCHNVGYKKMVLPNLLEHETMAEVKQQASSWVPLLNKNCHMGTQVFLCSLFAP 119

  Fly   445 PCDTHGSDLQPTPGQICREYCESFMAGCGGRLPQRFRQFF--------DCERFPES--------- 492
            .|       ...|...||..||:....|     :...|||        .|::|||.
  Rat   120 VC-------LDRPIYPCRWLCEAVRDSC-----EPVMQFFGFYWPEMLKCDKFPEGDVCIAMTPP 172

  Fly   493 --------TGTQSCHQKPHCVSDMQSNVQSPRLC 518
                    .||..|   |.|.::::|......||
  Rat   173 NATEASKPQGTTVC---PPCDNELKSEAIIEHLC 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	36/144 (25%)
		PRKCSH-like	<503..>582	CDD:193472	4/16 (25%)
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450
Sfrp1	NP_001263641.2	CRD_SFRP1	52..175	CDD:143552	34/131 (26%)
Sfrp1	NP_001263641.2	NTR_Sfrp1_like	183..306	CDD:239635	7/24 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900