DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and SFRP5

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_003006.2	Gene:	SFRP5 / 6425	HGNCID:	10779	Length:	317	Species:	Homo sapiens

Alignment Length:	124	Identity:	35/124 - (28%)
Similarity:	52/124 - (41%)	Gaps:	12/124 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 EPVVTTTPAPPRRC--SPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREA 434
            ||:...:.:.|.:|  .|.:|..|..|||.....||||.|.|..::.:....:..|:...||.:.
Human    40 EPLHGRSYSKPPQCLDIPADLPLCHTVGYKRMRLPNLLEHESLAEVKQQASSWLPLLAKRCHSDT 104

  Fly   435 YDFVCRLLQPPCDTHGSDLQPTPGQICREYCESFMAGCGGRLPQ---RFRQFFDCERFP 490
            ..|:|.|..|.|       ...|...||..||:..|||...:..   .:.:...|.:||
Human   105 QVFLCSLFAPVC-------LDRPIYPCRSLCEAVRAGCAPLMEAYGFPWPEMLHCHKFP 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	32/112 (29%)
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450
SFRP5	NP_003006.2	CRD_SFRP5	47..173	CDD:143553	33/117 (28%)
SFRP5	NP_003006.2	NTR_Sfrp1_like	178..303	CDD:239635
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5753
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.760