Protein Alignment CG1632 and fzd8b

DIOPT Version :10

• Sequence 1: NP_572467.1
• Gene: CG1632 / 31763
• FlyBaseID: FBgn0030027
• Length: 1056
• Species: Drosophila melanogaster
• Sequence 2: NP_571628.1
• Gene: fzd8b / 58072
• ZFINID: ZDB-GENE-000328-4
• Length: 576
• Species: Danio rerio
• Alignment Length: 255
• Identity: 61/255 - (23%)
• Similarity: 88/255 - (34%)
• Gaps: 70/255 - (27%)

  Fly   385 CSPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQPPC-DT 448
            |..:.:..||.:|||.|..||...|.:.::...:|..|..||:.:|..:...|:|.:..|.| :.
Zfish    31 CQEISVPLCRGIGYNYTYMPNQFNHDNQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLED 95

  Fly   449 HGSDLQPTPGQICREYCESFMAGC-------GGRLPQRFRQFFDCERFPESTGTQSCHQKPHCVS 506
            :...|.|     ||..||...|||       |...|.|.|    |:..|
Zfish    96 YKKPLPP-----CRSVCERAKAGCAPLMRQYGFPWPDRMR----CDLLP---------------- 135

  Fly   507 DMQSNVQSPRLCDGYADCPDLSDERSCAFCSPNA--LYCGRGRACVPRKARCDGKADCPDGADEK 569
             :|.:..:  ||..|        .|:.|..||.|  .....|:....:.....|.:.|     |.
Zfish   136 -VQGDPNT--LCMDY--------NRTDATSSPAAPKTTSRPGKPFKRKNKSSPGSSSC-----EP 184

  Fly   570 DCLSIAPLAADLLQPEPLV-----------------PYLSRFHSAGYAVFSEKGVVGKLC 612
            :|...||:........||.                 ||||: ....:|.| ..|:...||
Zfish   185 ECYCRAPMVPVHSDHHPLYNRVKTGQIPNCAMPCHNPYLSQ-EERTFATF-WIGIWSVLC 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_572467.1	SEA	232..>309	CDD:460188
		CRD_FZ	384..502	CDD:143549	34/124 (27%)
		PRKCSH-like	<503..>582	CDD:372423	16/80 (20%)
		LDLa	536..571	CDD:238060	7/36 (19%)
		Tryp_SPc	708..>809	CDD:473915
fzd8b	NP_571628.1	CRD_FZ8	27..151	CDD:143570	39/155 (25%)
		7tmF_FZD8	221..530	CDD:320378	9/24 (38%)
		TM helix 1	230..255	CDD:320378	5/14 (36%)
		TM helix 2	264..285	CDD:320378
		TM helix 3	314..336	CDD:320378
		TM helix 4	357..373	CDD:320378
		TM helix 5	395..418	CDD:320378
		TM helix 6	446..471	CDD:320378
		TM helix 7	491..516	CDD:320378