DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1632 and Fzd2

DIOPT Version :9

Sequence 1:NP_001245577.1 Gene:CG1632 / 31763 FlyBaseID:FBgn0030027 Length:1056 Species:Drosophila melanogaster
Sequence 2:NP_065256.1 Gene:Fzd2 / 57265 MGIID:1888513 Length:570 Species:Mus musculus


Alignment Length:238 Identity:64/238 - (26%)
Similarity:79/238 - (33%) Gaps:65/238 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   385 CSPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQPPCDTH 449
            |.|:.:..|..:.||.|..||||||.:.|....:|..|..||..:|..|...|:|.:..|.|...
Mouse    44 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVL 108

  Fly   450 GSDLQPTPGQICREYCESFMAGC-------GGRLPQRFRQFFDCERFPESTGTQSCHQKPHCVSD 507
            ...:.|     ||..||....||       |.:.|:|.|    ||.||.....|.      ||..
Mouse   109 EQAIPP-----CRSICERARQGCEALMNKFGFQWPERLR----CEHFPRHGAEQI------CVGQ 158

  Fly   508 MQSNVQSPRLCDGYADCPDLSDERSCAFCSPNALYCGR--------GRACVPRKARCDGKADCP- 563
            ..|...:|.|               .....|:.|..|.        |....||.|..:....|| 
Mouse   159 NHSEDGAPAL---------------LTTAPPSGLQPGAGGTPGGPGGGGSPPRYATLEHPFHCPR 208

  Fly   564 ----------DGADEKDCLSIAPLAADLLQPEPLVPYLSRFHS 596
                      ....|:||  .||.       ||..|..|.|.|
Mouse   209 VLKVPSYLSYKFLGERDC--AAPC-------EPARPDGSMFFS 242

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1632NP_001245577.1 SEA 232..327 CDD:279699
CRD_FZ 384..502 CDD:143549 39/123 (32%)
PRKCSH-like <503..>582 CDD:193472 19/97 (20%)
LDLa 536..571 CDD:238060 10/53 (19%)
Tryp_SPc 708..>809 CDD:304450
Fzd2NP_065256.1 CRD_FZ2 40..166 CDD:143573 42/136 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 166..194 6/42 (14%)
Frizzled 240..557 CDD:279827 2/3 (67%)
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 548..553
PDZ-binding 568..570
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3577
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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