DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and sfrp2

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001070852.2	Gene:	sfrp2 / 566878	ZFINID:	ZDB-GENE-061013-293	Length:	294	Species:	Danio rerio

Alignment Length:	168	Identity:	45/168 - (26%)
Similarity:	66/168 - (39%)	Gaps:	33/168 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 CSPL--ELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQPPC- 446
            |.|:  .|..|..:.|.....||||||.:..::.:....:..||..:||.:...|:|.|..|.|
Zfish    38 CKPIPTNLLLCHDIEYTNMRLPNLLGHETMNEVLQQASSWTPLVQKQCHPDTKKFLCSLFAPVCL 102

  Fly   447 DTHGSDLQPTPGQICREYCESFMAGC-------GGRLPQRFRQFFDCERFPESTGTQSCHQKPHC 504
            |.....:||     ||..|||..:||       |...|    ...||.|||.....        |
Zfish   103 DDLDEPIQP-----CRSLCESVKSGCAPVMAAFGFPWP----DMLDCRRFPLDNDL--------C 150

  Fly   505 VSDMQSNV------QSPRLCDGYADCPDLSDERSCAFC 536
            :....::.      :.||:||...:.|:..:|...:.|
Zfish   151 IPPAGADALVPVTKEVPRVCDACKEKPENDNEIVDSLC 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	37/126 (29%)
		PRKCSH-like	<503..>582	CDD:193472	8/40 (20%)
		LDLa	536..571	CDD:238060	1/1 (100%)
		Tryp_SPc	708..>809	CDD:304450
sfrp2	NP_001070852.2	CRD_SFRP2	34..161	CDD:143555	38/139 (27%)
sfrp2	NP_001070852.2	NTR_Sfrp1_like	167..294	CDD:239635	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900