DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and AgaP_AGAP005686

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	XP_001688706.1	Gene:	AgaP_AGAP005686 / 5667393	VectorBaseID:	AGAP005686	Length:	297	Species:	Anopheles gambiae

Alignment Length:	366	Identity:	69/366 - (18%)
Similarity:	116/366 - (31%)	Gaps:	164/366 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   710 PGDWPWLVAL---FREDIHVCDGTLITQDWVLTTEGCFQGQPRAT---WMAIVGAVRLSAKAPWT 768
            ||.:|:.|||   |.|...:|..:::|::::||...|..|...|.   .:||:||
Mosquito    65 PGQFPYQVALLSDFPEGTALCGASVLTRNFLLTAAHCISGTGNALSSGGIAIMGA---------- 119

  Fly   769 QRRRIIGMIKSPVEGSTA-----------------ALVRLETPVSYSDHVRPICLPDALQRRLLQ 816
            |.|.|:.:.:..:..||:                 |||.|.:.::::..|:||.||.....|
Mosquito   120 QNRMIVELSQQRIRFSTSGIRRHPGYDATSLRNDVALVLLNSRITFTSRVQPIRLPARTDTR--- 181

  Fly   817 QPPAQRRSHVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQEDHFGG 881
                                                                         .|||
Mosquito   182 -------------------------------------------------------------QFGG 185

  Fly   882 ESAASYMPKAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIA-TKAPILAAVPAAQEQI 945
            .:..            :.|:             ..:|.:|.:|:|.:. |..|:|
Mosquito   186 FTGT------------VSGF-------------GRTTDSSQATSATLRFTSNPVL---------- 215

  Fly   946 WTNCNTL-GWSRQRDHLQRVQLKMGDMAPCENVSIATVNSMCMEATYQKYDCTQEEYSGAPVQCL 1009
             ||...: .|                     ...:|...::|::|:..:..|..:  ||.|   |
Mosquito   216 -TNAECITSW---------------------GFGLAQSQNVCLKASGGRSACNGD--SGGP---L 253

  Fly  1010 IPGTNQWALIGVSSWRIACG-PTGVERPRMYDKIASNAAWI 1049
            ...:|....|||.|:..|.| .:|  ||.:|.::.....||
Mosquito   254 TVDSNGVLQIGVVSFVSAAGCASG--RPSVYARVTYFLPWI 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450	33/121 (27%)
AgaP_AGAP005686	XP_001688706.1	Tryp_SPc	56..292	CDD:214473	67/364 (18%)
AgaP_AGAP005686	XP_001688706.1	Tryp_SPc	57..295	CDD:238113	69/366 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910