Protein Alignment CG1632 and TMPRSS4

DIOPT Version :9

• Sequence 1: NP_001245577.1
• Gene: CG1632 / 31763
• FlyBaseID: FBgn0030027
• Length: 1056
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 114/540 - (21%)
• Similarity: 183/540 - (33%)
• Gaps: 207/540 - (38%)

  Fly   543 CGRGRACVPRKARCDGKADCPDGADEKDCLSIAPLAADLLQPEPLVPYLSRFHSAGYAVFSEKGV 607
            ||:....:|||..|||:.|||.|.||:.|:...|      :...:...||:..|....:.|..|.
Human    64 CGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFP------EGPAVAVRLSKDRSTLQVLDSATGN 122

  Fly   608 VGKLCAEGLEGDAKLVVRQTVSESLCKSLGYES------VEI-----FDVQNDTERLNDYVRVLD 661
            ....|.:..        .:.::|:.|:.:||.|      |||     .||...||...: :|:.:
Human   123 WFSACFDNF--------TEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQE-LRMRN 178

  Fly   662 PHAPEI--SFIRTHCPRRQVLYVGCGELRCGVQSALFNAKQHLSLPKM-----SAPGDWPWLVAL 719
            ...|.:  |.:..||            |.||         :.|..|::     ::...|||.|::
Human   179 SSGPCLSGSLVSLHC------------LACG---------KSLKTPRVVGVEEASVDSWPWQVSI 222

  Fly   720 FREDIHVCDGTLITQDWVLTTEGCFQGQPRA-TWMAIVGAVRLSAKAPWTQRRRIIGMIKSPV-- 781
            ..:..|||.|:::...||||...||:..... .|....|:.:|.: .|.....:||.:..:|:
Human   223 QYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKLGS-FPSLAVAKIIIIEFNPMYP 286

  Fly   782 EGSTAALVRLETPVSYSDHVRPICLPDALQRRLLQQPPAQRRSHVPVAERLEGQLVSQQRSRLSQ 846
            :.:..||::|:.|:::|..|||||||
Human   287 KDNDIALMKLQFPLTFSGTVRPICLP--------------------------------------- 312

  Fly   847 ENQQFFLIPSQEQQDSSTENQGDEDQDEQEDHFGGESAASYMPKAEALHQELDGYPLPDHAPQVN 911
                ||                    ||:
Human   313 ----FF--------------------DEE------------------------------------ 317

  Fly   912 YYSSSSTVTSSSTAARIATKAPILAAVPAAQEQIWTNCNTLGW-------SRQRDHLQRVQLKMG 969
                                  :..|.|     :|    .:||       .:..|.|.:..:::.
Human   318 ----------------------LTPATP-----LW----IIGWGFTKQNGGKMSDILLQASVQVI 351

  Fly   970 DMAPCENVSIA-----TVNSMCMEATYQKYDCTQEEYSGAPVQCLIPGTNQWALIGVSSWRIACG 1029
            |...| |...|     |...||........|..|.: ||.|   |:..::||.::|:.||...||
Human   352 DSTRC-NADDAYQGEVTEKMMCAGIPEGGVDTCQGD-SGGP---LMYQSDQWHVVGIVSWGYGCG 411

  Fly  1030 PTGVERPRMYDKIASNAAWI 1049
              |...|.:|.|:::...||
Human   412 --GPSTPGVYTKVSAYLNWI 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472	16/38 (42%)
		LDLa	536..571	CDD:238060	14/27 (52%)
		Tryp_SPc	708..>809	CDD:304450	33/103 (32%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060	14/27 (52%)
		SRCR_2	108..197	CDD:295335	22/109 (20%)
		Tryp_SPc	204..429	CDD:214473	68/362 (19%)
		Tryp_SPc	205..432	CDD:238113	70/363 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910