DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and frzb

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001005438.1	Gene:	frzb / 448021	XenbaseID:	XB-GENE-481353	Length:	319	Species:	Xenopus tropicalis

Alignment Length:	408	Identity:	74/408 - (18%)
Similarity:	133/408 - (32%)	Gaps:	137/408 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 CSPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQPPCDTH 449
            |.|:.:..|:.:.:|:|..||.|.|::.......:..|..|:..||.::...|:|.:..|.|..
Frog    31 CEPVRIPMCKSMPWNMTKMPNHLHHSTQANAILAIEQFEGLLTTECSQDLLFFLCAMYAPICTI- 94

  Fly   450 GSDLQPTPGQICREYCESFMAGCGGRLPQRFRQFFDCERFPESTGTQSCHQKPHCVSDMQSNVQS 514
              |.|..|.:.|:..||...|||...| .::|     ..:|||.   :|.:.|
Frog    95 --DFQHEPIKPCKSVCERARAGCEPIL-IKYR-----HTWPESL---ACEELP------------ 136

  Fly   515 PRLCDGYADCPDLSDERSCAFCSPNALYCGRGRACVPRKARCDGKADCPDGADEKDCLSIAPLAA 579
                        :.|...|  .||.|:        :..:...|...|.|..::..:|.|.|
Frog   137 ------------VYDRGVC--ISPEAI--------ITVEQGTDSMPDFPMDSNNGNCGSTA---- 175

  Fly   580 DLLQPEPLVPYLSRFHSAGYAVFSEKGVVGKLCAEGLEGDAKLVVRQTVSESLCKSLGYESVEIF 644
                                         |:.|.                   ||.:
Frog   176 -----------------------------GEHCK-------------------CKPM-------- 184

  Fly   645 DVQNDTERLNDYVRVLDPHAPEISFIRTHCPRRQVLYVGCGELRCGVQSALFNAKQHLSLPKMSA 709
            .....|...|:|..|:.....|:                  :::|...:|:...|:.|....::.
Frog   185 KASQKTYLKNNYNYVIRAKVKEV------------------KVKCHDATAIVEVKEILKSSLVNI 231

  Fly   710 PGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQGQPRATWMAIVGAV------RLSAKAP-W 767
            |.|   .|.|:.....:|...:..:::::..   ::.:.|...:.:.|::      ||:.|.. |
Frog   232 PKD---TVTLYTNSGCLCPQLVANEEYIIMG---YEDKERTRLLLVEGSLAEKWRDRLAKKVKRW 290

  Fly   768 TQRRRIIGMIKSPVEGST 785
            .|:.|.....|.||..:|
Frog   291 DQKLRRPRKSKDPVAQNT 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	32/116 (28%)
		PRKCSH-like	<503..>582	CDD:193472	11/78 (14%)
		LDLa	536..571	CDD:238060	6/34 (18%)
		Tryp_SPc	708..>809	CDD:304450	17/85 (20%)
frzb	NP_001005438.1	CRD_SFRP3	28..153	CDD:143550	38/167 (23%)
frzb	NP_001005438.1	NTR_Sfrp3_like	189..299	CDD:239636	22/133 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910