DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1632 and TMPRSS11F

DIOPT Version :9

Sequence 1:NP_001245577.1 Gene:CG1632 / 31763 FlyBaseID:FBgn0030027 Length:1056 Species:Drosophila melanogaster
Sequence 2:NP_997290.2 Gene:TMPRSS11F / 389208 HGNCID:29994 Length:438 Species:Homo sapiens


Alignment Length:383 Identity:76/383 - (19%)
Similarity:122/383 - (31%) Gaps:156/383 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   688 RCGVQSALFNAKQHLSLPKMSA------------PGDWPWLVAL-FREDIHVCDGTLITQDWVLT 739
            |||::....|    :.||..|:            .|:|||..:| .....|.|..:||:..|:||
Human   185 RCGIRMTSSN----MPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLT 245

  Fly   740 TEGCF-QGQPRATWMAIVGAVRLSAKAPWTQR--RRII--GMIKSPVEGSTAALVRLETPVSYSD 799
            ...|| :.:....|:|..||   :...|..:|  |:||  .........:..|||:|.|.|.:|:
Human   246 AAHCFWKNKDPTQWIATFGA---TITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSN 307

  Fly   800 HVRPICLPDALQRRLLQQPPAQRRSHVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSST 864
            .|:.:||||:    .::.||                                             
Human   308 IVQRVCLPDS----SIKLPP--------------------------------------------- 323

  Fly   865 ENQGDEDQDEQEDHFGGESAASYMPKAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIA 929
                                                             .:|..||...:   |.
Human   324 -------------------------------------------------KTSVFVTGFGS---IV 336

  Fly   930 TKAPILAAVPAAQEQIWTNCNTLGWSRQRDHLQRVQLKMGDMAPCENV--SIATVNSMCMEATYQ 992
            ...||.              |||   ||    .||:....|:...::|  .:.|...:|......
Human   337 DDGPIQ--------------NTL---RQ----ARVETISTDVCNRKDVYDGLITPGMLCAGFMEG 380

  Fly   993 KYDCTQEEYSGAPVQCLIPGTNQWALIGVSSWRIACG-PTGVERPRMYDKIASNAAWI 1049
            |.|..:.: ||.|:  :....:.|.::|:.||..:|. |   ::|.:|.::.....||
Human   381 KIDACKGD-SGGPL--VYDNHDIWYIVGIVSWGQSCALP---KKPGVYTRVTKYRDWI 432

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1632NP_001245577.1 SEA 232..327 CDD:279699
CRD_FZ 384..502 CDD:143549
PRKCSH-like <503..>582 CDD:193472
LDLa 536..571 CDD:238060
Tryp_SPc 708..>809 CDD:304450 35/118 (30%)
TMPRSS11FNP_997290.2 SEA 59..154 CDD:279699
Tryp_SPc 205..432 CDD:214473 67/357 (19%)
Tryp_SPc 206..435 CDD:238113 69/358 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165143829
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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