DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1632 and CG18477

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_609763.1	Gene:	CG18477 / 34922	FlyBaseID:	FBgn0028864	Length:	464	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	73/383 - (19%)
Similarity:	129/383 - (33%)	Gaps:	109/383 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   674 CPR-------RQVLYVGCGELRCGV---QSALFNAKQHLSLPKMSAPGDWPWLVALF--REDIHV 726
            ||:       |.::.....:.:||.   :...|:.::..:  .::...:.||:|||.  |...:|
  Fly    71 CPKNLIIKEPRLIINEPITDPQCGFVNSKGVTFSFREEDT--GLAQEAEVPWMVALLDARTSSYV 133

  Fly   727 CDGTLITQDWVLTTEGCFQGQPRATWMAIVGAVRLSAKAPWTQRRRIIGM-IKSPVE-------- 782
            ..|.||....|:|.....:....:..:...|....|.|   |::...:.: |:|.|.
  Fly   134 AGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTK---TEQLPSVDVPIRSIVRHPGFNLEN 195

  Fly   783 -GSTAALVRLETPVSYSDHVRPICLPDALQ-------------RRLLQQPP---AQRRSHVPVAE 830
             .:..|||.|...::.|.|:.|||:|.|.:             :.....|.   ..::..:||.:
  Fly   196 GANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIFTGWGKNSFDDPSYMNVLKKISLPVVQ 260

  Fly   831 RLEGQLVSQQRSRLSQEN----QQFFLIPSQEQQDSSTENQGD-------EDQDEQED-----HF 879
            |    ...:|:.||...|    ....:....|....|.|..|.       :|..::.:     :|
  Fly   261 R----RTCEQQLRLYYGNDFELDNSLMCAGGEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNF 321

  Fly   880 GGESAASYMPKAEALHQELD-----------GYPLPDHAPQVNYYSSSSTVTSSSTAARIATKAP 933
            |.:..   :|...|::..:.           ..|||:...:|.|.|                  |
  Fly   322 GVDCG---LPGVPAVYTNVANVIEWITLTTVNMPLPEEREEVPYAS------------------P 365

  Fly   934 ILAAVPAAQEQIWT------------NCNTLGWSRQRDHLQRVQLKMGDMAPCENVSI 979
            .|:|.|...:  |.            |.|::.|..|..:......:.....|.|||.|
  Fly   366 TLSAGPYLNQ--WNQPNYEWLPTGYPNVNSIPWQLQEANNDLANSQYVRYYPVENVGI 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450	29/112 (26%)
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:214473	47/240 (20%)
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:238113	47/240 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100