DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and gd

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001259479.1	Gene:	gd / 32159	FlyBaseID:	FBgn0000808	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	78/425 - (18%)
Similarity:	146/425 - (34%)	Gaps:	138/425 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   621 KLVVRQTVSESLCKSLGYESVEIFDVQNDTERLNDYV------RVLDPH-------------APE 666
            ||::....:..:|...|..|:.:..:|.:..|...::      .:|||.             .|.
  Fly   108 KLLLMSANNHVICFGSGEHSIFMTQIQLEHIRKLSFIPDKKSSLLLDPEEEEVRKTDDKPPSTPH 172

  Fly   667 ISFIR---THCP-----------------RRQVLYVGCGELRC--GVQSALF------NAKQHL- 702
            |.|.:   ...|                 |.:.|:|..||.:.  |:.|.:|      :..:|.
  Fly   173 IQFKKKPFAQAPKEICGRIDRDLDFHLSQRTESLHVAIGEPKSSDGITSPVFVDDDEDDVLEHQF 237

  Fly   703 ---------------SLPKMSAPGDWPWLVALFREDI----HVCDGTLITQDWVLTTEGCFQ-GQ 747
                           |||.::. |.||||.|::..::    ..|.|:|::...|:::..||: ..
  Fly   238 VDESEAEAIESDSADSLPSITR-GSWPWLAAIYVNNLTSLDFQCGGSLVSARVVISSAHCFKLFN 301

  Fly   748 PRATWMAIVGAVRLSAKAPWTQRRRIIGMIKSPVEG---------------STAALVRLETPVSY 797
            .|.|...::..:.......|.:.    |.:.:||:|               :..|::.|:..|.:
  Fly   302 KRYTSNEVLVFLGRHNLKNWNEE----GSLAAPVDGIYIHPDFNSQLSSYDADIAVIILKDEVRF 362

  Fly   798 SDHVRPICLPDALQRRLLQQPPAQRRSHVPVAERLEGQLV--SQQRSRLSQENQQFFLIPSQEQQ 860
            :..:||.||..           ...::...|.||  |.::  |..|:..:::.:....:|.::..
  Fly   363 NTFIRPACLWS-----------GSSKTEYIVGER--GIVIGWSFDRTNRTRDQKLSSELPGKKST 414

  Fly   861 DSSTEN------QGDEDQDEQEDHFGGESA-----ASYMPKAEALHQELDGYPLPDHAPQVNYYS 914
            |:|...      .|:.:......||...|:     |....:....||                 |
  Fly   415 DASAPKVVKAPIVGNAECFRANAHFRSLSSNRTFCAGIQAEERDTHQ-----------------S 462

  Fly   915 SSSTVTSSSTAA-------RIATKAPILAAVPAAQ 942
            .:|..|..|.|.       |...:..:.||:||.:
  Fly   463 GASIYTGISGAGLFIRRNNRWMLRGTVSAALPAVE 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450	26/120 (22%)
gd	NP_001259479.1	GD_N	27..124	CDD:292649	3/15 (20%)
		Tryp_SPc	257..526	CDD:238113	52/276 (19%)
		Tryp_SPc	258..526	CDD:214473	52/275 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100