DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and Mfrp

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001101607.1	Gene:	Mfrp / 315597	RGDID:	1307477	Length:	590	Species:	Rattus norvegicus

Alignment Length:	278	Identity:	63/278 - (22%)
Similarity:	108/278 - (38%)	Gaps:	71/278 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 YRERI---NLTLR-----RSDLREAYEG------SEILALDGSEDNNNIVV---HFNMIFDPYAG 310
            ||.|:   |.:|.     :.|..|.||.      |.:....|:|..:::|.   ...:||....|
  Rat   343 YRIRLEFHNFSLEEQTECKFDYVEVYEASNSGTFSSLGRFCGAEPPSHLVSSQHQLTVIFKTDLG 407

  Fly   311 LVSSGDLLALFH-----------------EEMTQPPQQR--RHFANMTVDVASLSIKETTGLIEE 356
             :|||..||.:.                 .|..|...:|  :...::..|.|:
  Rat   408 -ISSGGFLATYQAINTTESGCPWADLCGPREFCQSRVRRELQRICDLWKDCAN------------ 459

  Fly   357 PIMSSSPLGGHDETTEPVVTTTPAPPRRCSPLELSYCRQVGYNITTYPNL-LGHASYEQLAEDVI 420
              .|:.....|         .:|.....|.|:::..|..:.||.|.:||: :|.|:..::.:.:.
  Rat   460 --DSNDNCNSH---------LSPQLDLTCEPVQVEMCLGLSYNTTAFPNIWVGLATQMEVTDILR 513

  Fly   421 VFRELVDGECHREAYDFVCRLLQPPCDTHGSDLQPTPGQICRE---YCESFMAGCGGRLPQRFRQ 482
            .::.|....|::....|:|.||:|.|.:.|:.|.|. ..:|:|   .|:|.:|..|...|
  Rat   514 GYKSLTSLPCYQTFRRFLCGLLEPRCTSLGTILPPC-RSVCQEAEQQCQSSLALLGIPWP----- 572

  Fly   483 FFDCERFPESTGTQSCHQ 500
             |:|.|.|.....::|.|
  Rat   573 -FNCNRLPVPASLEACSQ 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699	22/97 (23%)
		CRD_FZ	384..502	CDD:143549	34/121 (28%)
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450
Mfrp	NP_001101607.1	CUB	150..258	CDD:238001
		LDLa	266..300	CDD:238060
		CUB	307..419	CDD:238001	21/76 (28%)
		Fz	477..579	CDD:279700	31/108 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900