DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and Prss22

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001100454.1	Gene:	Prss22 / 302971	RGDID:	1310880	Length:	307	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	79/359 - (22%)
Similarity:	128/359 - (35%)	Gaps:	132/359 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   708 SAPGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQG---QPRATWMAIVGAVRLSAKAPWTQ 769
            ||...|||:|::.:...|.|.|:|:|..||::...||..   :| :.:..::||.:|....|.:|
  Rat    56 SADAQWPWIVSILKNGSHHCAGSLLTNRWVVSAAHCFSSNMDKP-SPYSVLLGAWKLGNPGPRSQ 119

  Fly   770 RRRIIGMIKSP----VEGSTA--ALVRLETPVSYSDHVRPICLPDALQRRLLQQPPAQRRSHVPV 828
            :..|..::..|    .||:.|  ||||||.|:.:|:.:.||||||:             ..|:|
  Rat   120 KVGIASVLPHPRYSRKEGTHADIALVRLERPIQFSERILPICLPDS-------------SVHLP- 170

  Fly   829 AERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQEDHFGGESAASYMPKAEA 893
                              .|...::......|
  Rat   171 ------------------PNTNCWIAGWGSIQ--------------------------------- 184

  Fly   894 LHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIATKAPILAAVPAAQEQIWTNCNTLGWSRQR 958
                 ||.|||  .||              |..::  |.||:      ..::   |.:|.|.
  Rat   185 -----DGVPLP--RPQ--------------TLQKL--KVPII------DPEL---CKSLYWR--- 214

  Fly   959 DHLQRVQLKMGDMAPCENVSIATVNSMCMEATYQKYD-CTQEEYSGAPVQCLIPGTNQWALIGVS 1022
                    ..|..|..|::       :|......|.| |..:  ||.|:.|.:  .:.|.|.|:.
  Rat   215 --------GAGQEAITEDM-------LCAGYLEGKRDACLGD--SGGPLMCQV--DDHWLLTGII 260

  Fly  1023 SWRIACGPTGVERPRMYDKIASNAAWIRETISAI 1056
            ||...|...  .||.:|..:.::..|::..:..:
  Rat   261 SWGEGCAER--NRPGVYTSLLAHRPWVQRIVQGV 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450	39/109 (36%)
Prss22	NP_001100454.1	Tryp_SPc	49..285	CDD:214473	78/350 (22%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	79/353 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337594
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930