DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1632 and Frzb

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001093997.1	Gene:	Frzb / 295691	RGDID:	1311315	Length:	323	Species:	Rattus norvegicus

Alignment Length:	408	Identity:	75/408 - (18%)
Similarity:	132/408 - (32%)	Gaps:	142/408 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 CSPLELSYCRQVGYNITTYPNLLGHASYEQLAEDVIVFRELVDGECHREAYDFVCRLLQPPCDTH 449
            |.|:.:..|:.:.:|:|..||.|.|::.......:..|..|:...|..:...|:|.:..|.|..
  Rat    35 CEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHCSPDLLFFLCAMYAPICTI- 98

  Fly   450 GSDLQPTPGQICREYCESFMAGCGGRLPQRFRQFFDCERFPESTGTQSCHQKPHCVSDMQSNVQS 514
              |.|..|.:.|:..||....||...| .::|     ..:|||.   :|.:.|
  Rat    99 --DFQHEPIKPCKSVCERARQGCEPIL-IKYR-----HSWPESL---ACEELP------------ 140

  Fly   515 PRLCDGYADCPDLSDERSCAFCSPNALYCGRGRACVPRKARCDGKADCPDGADEKDCLSIAPLAA 579
                        :.|...|  .||.|:...                   ||||       .|:.:
  Rat   141 ------------VYDRGVC--ISPEAIVTA-------------------DGAD-------FPMDS 165

  Fly   580 DLLQPEPLVPYLSRFHSAGYAVFSEKGVVGKLCAEGLEGDAKLVVRQTVSESLCKSLGYESVEIF 644
                            |.|:.                        |.|.||. ||.....:.:
  Rat   166 ----------------STGHC------------------------RGTSSER-CKCKPVRATQ-- 187

  Fly   645 DVQNDTERLNDYVRVLDPHAPEISFIRTHCPRRQVLYVGCGELRCGVQSALFNAKQHLSLPKMSA 709
                .|...|:|..|:.....|:                  :::|...:|:...|:.|....::.
  Rat   188 ----KTYFRNNYNYVIRAKVKEV------------------KMKCHDVTAIVEVKEILKASLVNI 230

  Fly   710 PGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQGQPRATWMAIVGAV------RLSAKAP-W 767
            |.|   .|.|:.....:|....:.:::|:..   ::.:.|:..:.:.|::      ||..|.. |
  Rat   231 PRD---TVNLYSTSGCLCPPLSVNEEYVIMG---YEDEERSRLLLVEGSIAEKWKDRLGKKVKRW 289

  Fly   768 TQRRRIIGMIKSPVEGST 785
            ..:.|.:|:.|:....||
  Rat   290 DMKLRHLGLGKTDASDST 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549	30/116 (26%)
		PRKCSH-like	<503..>582	CDD:193472	10/78 (13%)
		LDLa	536..571	CDD:238060	7/34 (21%)
		Tryp_SPc	708..>809	CDD:304450	17/85 (20%)
Frzb	NP_001093997.1	CRD_SFRP3	32..157	CDD:143550	36/178 (20%)
Frzb	NP_001093997.1	NTR_Sfrp3_like	188..297	CDD:239636	22/132 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900