DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1632 and Hpn

DIOPT Version :9

Sequence 1:NP_001245577.1 Gene:CG1632 / 31763 FlyBaseID:FBgn0030027 Length:1056 Species:Drosophila melanogaster
Sequence 2:XP_038958880.1 Gene:Hpn / 29135 RGDID:61982 Length:559 Species:Rattus norvegicus


Alignment Length:495 Identity:104/495 - (21%)
Similarity:161/495 - (32%) Gaps:204/495 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   618 GDAKLVVRQTVSES---LCKS--------LGYESVEI--------FDVQ----NDT--------- 650
            ||::|:|......:   ||.|        ||.|.:..        .||:    |.|         
  Rat   100 GDSRLLVLDKTEGTWRLLCSSRSNARVAGLGCEEMGFLRALAHSELDVRTAGANGTSGFFCVDEG 164

  Fly   651 -----ERLNDYVRVLDPHAPEISFIRTHCPRRQVLYVGCGELRCGVQSALFNAKQHLSLPKM--- 707
                 :||.|.:.|.|            |||.:.|...|.:  ||        ::.|.:.::   
  Rat   165 GLPLAQRLLDVISVCD------------CPRGRFLTATCQD--CG--------RRKLPVDRIVGG 207

  Fly   708 --SAPGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQGQPR--ATWMAIVGAV-RLSAKAPW 767
              |:.|.|||.|:|..:..|:|.|:|::.|||||...||..:.|  :.|....||| |.|..|..
  Rat   208 QDSSLGRWPWQVSLRYDGTHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVARTSPHAVQ 272

  Fly   768 TQRRRII---GMI--KSPV---EGSTAALVRLETPVSYSDHVRPICLPDALQRRLLQQPPAQRRS 824
            ...:.:|   |.:  :.|.   ..:..|||.|.:.:..:::::|:|||.|               
  Rat   273 LGVQAVIYHGGYLPFRDPTIDENSNDIALVHLSSSLPLTEYIQPVCLPAA--------------- 322

  Fly   825 HVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQEDHFGGESAASYMP 889
                     ||.:                                                    
  Rat   323 ---------GQAL---------------------------------------------------- 326

  Fly   890 KAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIATKAPIL--AAVPAAQEQIWTNCNTL 952
                    :||              ...|||..........:|.:|  |.||....::   ||:.
  Rat   327 --------VDG--------------KVCTVTGWGNTQFYGQQAVVLQEARVPIISNEV---CNSP 366

  Fly   953 GWSRQRDHLQRVQLKMGDMAPCENVSIATVNSMCMEATYQKYDCTQEEYSGAPVQC--LIPGTNQ 1015
            .:     :..:::.||                .|........|..|.: ||.|..|  .|.||::
  Rat   367 DF-----YGNQIKPKM----------------FCAGYPEGGIDACQGD-SGGPFVCEDRISGTSR 409

  Fly  1016 WALIGVSSWRIACGPTGVERPRMYDKIASNAAWIRETISA 1055
            |.|.|:.||...|..  ..:|.:|.|:.....||.:.|.|
  Rat   410 WRLCGIVSWGTGCAL--ARKPGVYTKVIDFREWIFQAIKA 447

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1632NP_001245577.1 SEA 232..327 CDD:279699
CRD_FZ 384..502 CDD:143549
PRKCSH-like <503..>582 CDD:193472
LDLa 536..571 CDD:238060
Tryp_SPc 708..>809 CDD:304450 37/111 (33%)
HpnXP_038958880.1 Hepsin-SRCR 92..200 CDD:401275 26/121 (21%)
Tryp_SPc 204..441 CDD:238113 73/361 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337604
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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