DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_001008554.1	Gene:	Tmprss11g / 289546	RGDID:	1306446	Length:	417	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	66/366 - (18%)
Similarity:	114/366 - (31%)	Gaps:	164/366 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   706 KMSAPGDWPWLVALFREDIHVCDGTLITQDWVLTTEGCFQG--QPRATWMAIVGAVRLSAKAPWT 768
            |.:....|||..:|..|.||:|..:||...|::|:..||..  .|: .|....|.   :...|.|
  Rat   190 KPAGSNSWPWQSSLQVEGIHLCGASLIGSQWLVTSAHCFDNYKNPK-LWTVSFGR---TLGNPLT 250

  Fly   769 QRRRIIGMIKSPV--EGSTA-------ALVRLETPVSYSDHVRPICLPDALQRRLLQQPPAQRRS 824
            .|:     ::|.:  |...|       |:|:|.:||.:|:::|.:|||
  Rat   251 TRK-----VESIIIHENYAAHKHDDDIAVVKLSSPVLFSENLRTVCLP----------------- 293

  Fly   825 HVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQDSSTENQGDEDQDEQEDHFGGESAASYMP 889
                                                                     |:....:|
  Rat   294 ---------------------------------------------------------EATFQVLP 301

  Fly   890 KAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTAARIATKAPILAAVPAAQEQIWTNCNTLGW 954
            |::..                        ||                                ||
  Rat   302 KSKVF------------------------VT--------------------------------GW 310

  Fly   955 SRQR------DHLQRVQLKMGDMAPCENVSI--ATVNS--MCMEATYQKYDCTQEEYSGAPVQCL 1009
            ...:      :.||.|::::.....|..|::  ..::|  :|......|.|..:.: ||.|: .:
  Rat   311 GALKANGPFPNSLQEVEIEIISNDVCNQVNVYGGAISSGMICAGFLTGKLDACEGD-SGGPL-VI 373

  Fly  1010 IPGTNQWALIGVSSWRIACGPTGVERPRMYDKIASNAAWIR 1050
            ....|:|.|:|:.||.|.||..  .:|.:|.::.....||:
  Rat   374 SDNRNKWYLLGIVSWGIDCGKE--NKPGIYTRVTHYRNWIK 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450	33/111 (30%)
Tmprss11g	NP_001008554.1	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	64/363 (18%)
		Tryp_SPc	186..414	CDD:238113	66/366 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337591
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930