DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1632 and Fzd6

DIOPT Version :9

Sequence 1:NP_001245577.1 Gene:CG1632 / 31763 FlyBaseID:FBgn0030027 Length:1056 Species:Drosophila melanogaster
Sequence 2:NP_001124008.1 Gene:Fzd6 / 282581 RGDID:628816 Length:710 Species:Rattus norvegicus


Alignment Length:325 Identity:77/325 - (23%)
Similarity:117/325 - (36%) Gaps:107/325 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   359 MSSSP----------LGGHDETTEPVVTTTPAPPRRCSPLELSYCRQVGYNITTYPNLLGHASYE 413
            |.:||          :.||...|             |.|:.:..|.::.||:|.:|||:||  |:
  Rat     1 MEASPFLSACILLPLIRGHSLFT-------------CEPITVPRCMKMAYNMTFFPNLMGH--YD 50

  Fly   414 Q--LAEDVIVFRELVDGECHREAYDFVCRLLQPPCDTHGSDLQPTPGQICREYCESFMAGCGGRL 476
            |  .|.::..|..|.:.||......|:|:...|.|......:.|     ||:.||..::.|    
  Rat    51 QGIAAVEMEHFLPLANLECSPNIEMFLCQAFVPTCTEQIDVVSP-----CRKLCEKILSDC---- 106

  Fly   477 PQRFRQFFDCERFPESTGTQSCHQKPHC------VSDMQSNVQSPRLCDGYADCPDLSDE--RSC 533
             |:....|.. |:||..   .||:.|:|      .||..:.:..|:         ..:|:  |..
  Rat   107 -QKLMDTFGI-RWPEEL---ECHRLPYCDGAVPVTSDPHTELFGPQ---------KKTDQVPRDI 157

  Fly   534 AFCSPNALYCGRGRA--------CVPRKARCDGKADCPD---GADEKD-------CLSIAPLAAD 580
            .|..|..|.....:.        |.|         .||:   .:||.|       .:||..|.|.
  Rat   158 GFWCPKHLRTSGDQGYRFLGIDQCAP---------PCPNMYFKSDELDFAKSFIGIVSIFCLCAT 213

  Fly   581 LL-------------QPE-PLVPYLSRFHSAGYAVFSEKGVVGKLCAEGL---EGDAKLVVRQTV 628
            |.             .|| |::     ::|..|::.|....||.|.....   :.|.||.:..||
  Rat   214 LFTFLTFLIDVRRFRYPERPII-----YYSVCYSIVSLMYFVGFLLGNSTACNKADEKLELGNTV 273

  Fly   629  628
              Rat   274  273

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1632NP_001245577.1 SEA 232..327 CDD:279699
CRD_FZ 384..502 CDD:143549 35/119 (29%)
PRKCSH-like <503..>582 CDD:193472 20/104 (19%)
LDLa 536..571 CDD:238060 9/52 (17%)
Tryp_SPc 708..>809 CDD:304450
Fzd6NP_001124008.1 CRD_FZ6 20..146 CDD:143559 40/154 (26%)
7tmF_FZD6 188..508 CDD:320160 22/91 (24%)
TM helix 1 198..222 CDD:320160 5/23 (22%)
TM helix 2 231..252 CDD:320160 6/25 (24%)
TM helix 3 283..305 CDD:320160
TM helix 4 326..342 CDD:320160
TM helix 5 364..387 CDD:320160
TM helix 6 418..440 CDD:320160
TM helix 7 469..494 CDD:320160
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3577
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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