DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1632 and Tmprss11f

DIOPT Version :9

Sequence 1:	NP_001245577.1	Gene:	CG1632 / 31763	FlyBaseID:	FBgn0030027	Length:	1056	Species:	Drosophila melanogaster
Sequence 2:	NP_848845.1	Gene:	Tmprss11f / 243083	MGIID:	2442348	Length:	439	Species:	Mus musculus

Alignment Length:	387	Identity:	74/387 - (19%)
Similarity:	124/387 - (32%)	Gaps:	164/387 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   688 RCGVQSALFNAKQHLSLPKMSA------------PGDWPWLVALFREDI---HVCDGTLITQDWV 737
            |||::.:..|    :.||..|:            .|:|||..:|  :.|   |.|..|||:..|:
Mouse   186 RCGIRMSSSN----IPLPASSSTERIVQGRETAMEGEWPWQASL--QLIGAGHQCGATLISNTWL 244

  Fly   738 LTTEGCF-QGQPRATWMAIVGAVRLSAKAPWTQRRRIIGMI------KSPVEGSTAALVRLETPV 795
            ||...|| :.:....|:...|.   :...|..  :|.:|.|      ......:..||.:|.|.|
Mouse   245 LTAAHCFWKNRDPTKWIVTFGT---TITPPLV--KRSVGKIIIHEEYHRDTNENDIALAQLTTRV 304

  Fly   796 SYSDHVRPICLPDALQRRLLQQPPAQRRSHVPVAERLEGQLVSQQRSRLSQENQQFFLIPSQEQQ 860
            .:|:.|:.:||||:    .::.||   ::.|.|..  .|.:|                      .
Mouse   305 EFSNVVQRVCLPDS----SMKLPP---KTSVFVTG--FGSIV----------------------D 338

  Fly   861 DSSTENQGDEDQDEQEDHFGGESAASYMPKAEALHQELDGYPLPDHAPQVNYYSSSSTVTSSSTA 925
            |..|:|:                          |.|
Mouse   339 DGPTQNK--------------------------LRQ----------------------------- 348

  Fly   926 ARIATKAPILAAVPAAQEQIWTNCNTLGWSRQRDHLQRVQLKMGDMAPCENV--SIATVNSMCME 988
            ||:                     .|:|               .|:...::|  .:.|...:|..
Mouse   349 ARV---------------------ETIG---------------SDVCNRKDVYDGLITPGMLCAG 377

  Fly   989 ATYQKYDCTQEEYSGAPVQCLIPGTNQWALIGVSSWRIACG-PTGVERPRMYDKIASNAAWI 1049
            ....|.|..:.: ||.|:  :....:.|.::|:.||..:|. |   .:|.:|.::.....||
Mouse   378 FMEGKIDACKGD-SGGPL--VYDNRDIWYIVGIVSWGQSCALP---NKPGVYTRVTKYRDWI 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1632	NP_001245577.1	SEA	232..327	CDD:279699
		CRD_FZ	384..502	CDD:143549
		PRKCSH-like	<503..>582	CDD:193472
		LDLa	536..571	CDD:238060
		Tryp_SPc	708..>809	CDD:304450	33/122 (27%)
Tmprss11f	NP_848845.1	SEA	60..164	CDD:396113
Tmprss11f	NP_848845.1	Tryp_SPc	207..436	CDD:238113	67/362 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834067
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930